M. Bauer, T. Glenn, E. D. Achtyes, M. Alda, E. Agaoglu, K. Altınbaş, O. A. Andreassen, E. Angelopoulos, R. Ardau, M. Aydin, Y. Ayhan, C. Baethge, R. Bauer, B. T. Baune, C. Balaban, C. Becerra-Palars, A. P. Behere, H. Belete, T. Belete, G. Okawa Belizario, F. Bellivier, R. H. Belmaker, F. Benedetti, M. Berk, Y. Bersudsky, Ş. Bicakci, H. Birabwa-Oketcho, T. D. Bjella, C. Brady, J. Cabrera, M. Cappucciati, A. M. Paredes Castro, W. Chen, E. Y. W. Cheung, S. Chiesa, M. Chanopoulou, M. Crowe, A. Cuomo, S. Dallaspezia, P. Desai, S. Dodd, B. Etain, A. Fagiolini, F. T. Fellendorf, E. Ferensztajn-Rochowiak, J. G. Fiedorowicz, K. N. Fountoulakis, M. A. Frye, P. A. Geoffroy, M. J. Gitlin, A. Gonzalez-Pinto, J. F. Gottlieb, P. Grof, B. C. M. Haarman, H. Harima, M. Hasse-Sousa, C. Henry, L. Hoffding, J. Houenou, M. Imbesi, E. T. Isometsä, M. Ivkovic, S. Janno, S. Johnsen, F. Kapczinski, G. N. Karakatsoulis, M. Kardell, L. V. Kessing, S. J. Kim, B. König, T. L. Kot, M. Koval, M. Kunz, B. Lafer, M. Landén, E. R. Larsen, R. W. Licht, V. M. Ludwig, C. Lopez-Jaramillo, A. MacKenzie, H. Østergaard Madsen, S. Alberte Kongstad A. Madsen, J. Mahadevan, A. Mahardika, K. Mahfoudh, M. Manchia, W. Marsh, M. Martinez-Cengotitabengoa, J. Martini, K. Martiny, Y. Mashima, D. M. McLoughlin, A. N. R. Meesters, Y. Meesters, I. Melle, F. Meza-Urzúa, E. Michaelis, P. Mikolas, Y. Ming Mok, S. Monteith, M. Moorthy, G. Morken, E. Mosca, A. A. Mozzhegorov, R. Munoz, S. V. Mythri, R. K. Nadella, T. Nakanotani, R. Ernst Nielsen, C. O'Donovan, A. Omrani, Y. Osher, U. Ouali, M. Pantovic-Stefanovic, P. Pariwatcharakul, J. Petite, A. Pfennig, M. Pilhatsch, Y. Pica Ruiz, M. Pinna, M. Pompili, R. Porter, D. Quiroz, F. Diego Rabelo-da-Ponte, R. Ramesar, N. Rasgon, W. Ratta-apha, M. Redahan, M. S. Reddy, A. Reif, E. Z. Reininghaus, J. Gringer Richards, P. Ritter, J. K. Rybakowski, L. Sathyaputri, A. M. Scippa, C. Simhandl, D. Smith, J. Smith, P. W. Stackhouse Jr, D. J. Stein, K. Stilwell, S. Strejilevich, K.-P. Su, M. Subramaniam, A. Hatim Sulaiman, K. Suominen, A. J. Tanra, Y. Tatebayashi, W. Lin Teh, L. Tondo, C. Torrent, D. Tuinstra, T. Uchida, A. E. Vaaler, E. Vieta, B. Viswanath, C. Volf, K.-J. Yang, M. Yoldi-Negrete, O. Kaan Yalcinkaya, A. H. Young, Y. Zgueb, P. C. Whybrow
{"title":"Family History and Solar Insolation in Bipolar I Disorder","authors":"M. Bauer, T. Glenn, E. D. Achtyes, M. Alda, E. Agaoglu, K. Altınbaş, O. A. Andreassen, E. Angelopoulos, R. Ardau, M. Aydin, Y. Ayhan, C. Baethge, R. Bauer, B. T. Baune, C. Balaban, C. Becerra-Palars, A. P. Behere, H. Belete, T. Belete, G. Okawa Belizario, F. Bellivier, R. H. Belmaker, F. Benedetti, M. Berk, Y. Bersudsky, Ş. Bicakci, H. Birabwa-Oketcho, T. D. Bjella, C. Brady, J. Cabrera, M. Cappucciati, A. M. Paredes Castro, W. Chen, E. Y. W. Cheung, S. Chiesa, M. Chanopoulou, M. Crowe, A. Cuomo, S. Dallaspezia, P. Desai, S. Dodd, B. Etain, A. Fagiolini, F. T. Fellendorf, E. Ferensztajn-Rochowiak, J. G. Fiedorowicz, K. N. Fountoulakis, M. A. Frye, P. A. Geoffroy, M. J. Gitlin, A. Gonzalez-Pinto, J. F. Gottlieb, P. Grof, B. C. M. Haarman, H. Harima, M. Hasse-Sousa, C. Henry, L. Hoffding, J. Houenou, M. Imbesi, E. T. Isometsä, M. Ivkovic, S. Janno, S. Johnsen, F. Kapczinski, G. N. Karakatsoulis, M. Kardell, L. V. Kessing, S. J. Kim, B. König, T. L. Kot, M. Koval, M. Kunz, B. Lafer, M. Landén, E. R. Larsen, R. W. Licht, V. M. Ludwig, C. Lopez-Jaramillo, A. MacKenzie, H. Østergaard Madsen, S. Alberte Kongstad A. Madsen, J. Mahadevan, A. Mahardika, K. Mahfoudh, M. Manchia, W. Marsh, M. Martinez-Cengotitabengoa, J. Martini, K. Martiny, Y. Mashima, D. M. McLoughlin, A. N. R. Meesters, Y. Meesters, I. Melle, F. Meza-Urzúa, E. Michaelis, P. Mikolas, Y. Ming Mok, S. Monteith, M. Moorthy, G. Morken, E. Mosca, A. A. Mozzhegorov, R. Munoz, S. V. Mythri, R. K. Nadella, T. Nakanotani, R. Ernst Nielsen, C. O'Donovan, A. Omrani, Y. Osher, U. Ouali, M. Pantovic-Stefanovic, P. Pariwatcharakul, J. Petite, A. Pfennig, M. Pilhatsch, Y. Pica Ruiz, M. Pinna, M. Pompili, R. Porter, D. Quiroz, F. Diego Rabelo-da-Ponte, R. Ramesar, N. Rasgon, W. Ratta-apha, M. Redahan, M. S. Reddy, A. Reif, E. Z. Reininghaus, J. Gringer Richards, P. Ritter, J. K. Rybakowski, L. Sathyaputri, A. M. Scippa, C. Simhandl, D. Smith, J. Smith, P. W. Stackhouse Jr, D. J. Stein, K. Stilwell, S. Strejilevich, K.-P. Su, M. Subramaniam, A. Hatim Sulaiman, K. Suominen, A. J. Tanra, Y. Tatebayashi, W. Lin Teh, L. Tondo, C. Torrent, D. Tuinstra, T. Uchida, A. E. Vaaler, E. Vieta, B. Viswanath, C. Volf, K.-J. Yang, M. Yoldi-Negrete, O. Kaan Yalcinkaya, A. H. Young, Y. Zgueb, P. C. Whybrow","doi":"10.1111/acps.70075","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Sunlight has profound impacts on physical and mental health, beyond vision, including effects on circadian rhythms, alertness, mood, and sleep. A family history of any mood disorders is strongly associated with psychiatric disorders including bipolar disorder. The purpose of this study was to evaluate the association between a family history of any mood disorder in patients with bipolar I disorder and solar insolation at varied international onset locations.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Data for this analysis were available from 5842 patients with a diagnosis of bipolar I disorder obtained at 83 collection sites in both hemispheres. This included 4752 patients from 71 collection sites in the northern hemisphere and 1090 patients from 12 collection sites in the southern hemisphere. Patient data variables were obtained from records or interviews. Solar insolation data were obtained from The National Aeronautics and Space Administration (NASA) Power database for each onset location, and the ratio of the mean monthly minimum/mean monthly maximum solar insolation was calculated. Typically, the ratio is largest near the equator (little yearly change in solar insolation) and smallest near the poles (large yearly change in solar insolation).</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>A significant relationship was found between a family history of any mood disorder, the ratio of the mean monthly minimum/mean monthly maximum solar insolation, and gender. The odds of a family history of mood disorder increased as patient location nears the poles and decreased near the equator. Female gender also increased the odds of having a family history of a mood disorder.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>This study highlighted the association between family history, solar insolation, and gender in international patients with bipolar I disorder. Given the profound effects of sunlight on human health, the family of patients with bipolar disorder who live in the same location with the same solar insolation, and especially females, may be at increased risk for a mood disorder.</p>\n </section>\n </div>","PeriodicalId":108,"journal":{"name":"Acta Psychiatrica Scandinavica","volume":"153 4","pages":"270-278"},"PeriodicalIF":4.7000,"publicationDate":"2026-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12967720/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Psychiatrica Scandinavica","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/acps.70075","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/2/24 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Sunlight has profound impacts on physical and mental health, beyond vision, including effects on circadian rhythms, alertness, mood, and sleep. A family history of any mood disorders is strongly associated with psychiatric disorders including bipolar disorder. The purpose of this study was to evaluate the association between a family history of any mood disorder in patients with bipolar I disorder and solar insolation at varied international onset locations.
Methods
Data for this analysis were available from 5842 patients with a diagnosis of bipolar I disorder obtained at 83 collection sites in both hemispheres. This included 4752 patients from 71 collection sites in the northern hemisphere and 1090 patients from 12 collection sites in the southern hemisphere. Patient data variables were obtained from records or interviews. Solar insolation data were obtained from The National Aeronautics and Space Administration (NASA) Power database for each onset location, and the ratio of the mean monthly minimum/mean monthly maximum solar insolation was calculated. Typically, the ratio is largest near the equator (little yearly change in solar insolation) and smallest near the poles (large yearly change in solar insolation).
Results
A significant relationship was found between a family history of any mood disorder, the ratio of the mean monthly minimum/mean monthly maximum solar insolation, and gender. The odds of a family history of mood disorder increased as patient location nears the poles and decreased near the equator. Female gender also increased the odds of having a family history of a mood disorder.
Conclusions
This study highlighted the association between family history, solar insolation, and gender in international patients with bipolar I disorder. Given the profound effects of sunlight on human health, the family of patients with bipolar disorder who live in the same location with the same solar insolation, and especially females, may be at increased risk for a mood disorder.
期刊介绍：
Acta Psychiatrica Scandinavica acts as an international forum for the dissemination of information advancing the science and practice of psychiatry. In particular we focus on communicating frontline research to clinical psychiatrists and psychiatric researchers.
Acta Psychiatrica Scandinavica has traditionally been and remains a journal focusing predominantly on clinical psychiatry, but translational psychiatry is a topic of growing importance to our readers. Therefore, the journal welcomes submission of manuscripts based on both clinical- and more translational (e.g. preclinical and epidemiological) research. When preparing manuscripts based on translational studies for submission to Acta Psychiatrica Scandinavica, the authors should place emphasis on the clinical significance of the research question and the findings. Manuscripts based solely on preclinical research (e.g. animal models) are normally not considered for publication in the Journal.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
