Maternal vaginal colonisation with Neisseria meningitidis serogroup B and late onset neonatal invasive meningococcal disease.

Abstract

Here we report a case of late onset neonatal invasive meningococcal disease that was vertically transmitted, with maternal vaginal swab at the time of delivery and neonatal cerebrospinal fluid culture positive for Neisseria meningitidis. Whole genome sequencing of meningococcal isolates in the neonatal cerebrospinal fluid and maternal vaginal found both Men-B ST-2506 (clonal complex 32) and identical (1 SNP difference on split kmer analysis).