[Sarcomas : Clinical introduction].

IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-05-01 Epub Date: 2026-02-23 DOI:10.1007/s00117-026-01581-y
Lars H Lindner
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引用次数: 0

Abstract

Sarcomas are malignant tumors of connective and supporting tissues characterized by substantial biological and clinical heterogeneity. Their optimal treatment requires specialized expertise, particularly in radiological diagnostics. The correct interpretation of imaging procedures represents the first crucial step in treatment planning. Radiologists play a key role by recognizing suspicious findings and initiating early referral to specialized sarcoma centers. Depending on the histological subtype, sarcomas require tailored imaging strategies. A notable example is whole-body magnetic resonance imaging (MRI) for the detection of osseous metastases in myxoid liposarcoma. The assessment of treatment response in the neoadjuvant setting also poses a particular challenge as it is not uncommon for treatment-related imaging changes to mimic tumor progression (pseudoprogression) and must be reliably distinguished from true progression. During follow-up an appropriate balance between oncologic safety, such as early detection of local recurrence or metastases, and minimizing cumulative radiation exposure must be achieved.

【肉瘤:临床介绍】。
肉瘤是结缔组织和支持组织的恶性肿瘤,具有生物学和临床异质性。他们的最佳治疗需要专门的专业知识,特别是放射诊断。正确解释成像程序是制定治疗计划的关键第一步。放射科医生通过识别可疑的发现和开始早期转诊到专门的肉瘤中心发挥关键作用。根据组织学亚型,肉瘤需要量身定制的成像策略。一个值得注意的例子是全身磁共振成像(MRI)用于检测黏液样脂肪肉瘤的骨转移。在新辅助治疗中评估治疗反应也提出了一个特别的挑战,因为与治疗相关的影像学改变模拟肿瘤进展(假进展)并不罕见,必须可靠地与真正的进展区分开来。在随访期间,必须在肿瘤安全性(如早期发现局部复发或转移)和最小化累积辐射暴露之间取得适当的平衡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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