A Rare Case of Secondary Pseudotumor Cerebri Syndrome in a Female with a Tongue Base Tumor: A Case Report.

IF 0.4 Q4 CLINICAL NEUROLOGY

Case Reports in Neurology Pub Date : 2026-01-09 eCollection Date: 2026-01-01 DOI:10.1159/000549878

Sophie Bryde Laursen, Marianne Wegener, Emil Andonov Smilkov, Faezeh Nemati Karimooy, Rigmor Højland Jensen, Nadja Skadkær Hansen

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引用次数: 0

Abstract

Introduction: The pseudotumor cerebri syndrome (PTCS) is characterized by elevated intracranial pressure in the absence of intracranial structural lesions, with normal cerebrospinal fluid. PTCS may be primary, also known as idiopathic intracranial hypertension (IIH), or secondary to an identifiable cause such as obstructive sleep apnea (OSA). Primary and secondary PTCS share similar clinical features.

Case presentation: We report the case of a 43-year-old female of normal weight initially suspected of IIH, who was subsequently diagnosed with secondary PTCS caused by a tongue base tumor, leading to OSA. She presented with symptoms consistent with PTCS, including headache, transient visual obscurations, and progressive visual decline. Fundoscopy revealed severe bilateral papilledema, and lumbar puncture showed an opening pressure of 43 cm H₂O. Despite treatment with acetazolamide, her vision worsened, and optic nerve sheath fenestration was performed. Further investigation identified OSA caused by a benign tumor of the tongue as the underlying etiology. Following continuous positive airway pressure therapy her headache and papilledema resolved.

Conclusion: The case illustrates the importance of thorough search for secondary causes in patients diagnosed with PTCS.

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女性舌底肿瘤继发性脑假瘤综合征1例报告。

简介：假性脑瘤综合征（PTCS）的特征是在颅内无结构性病变的情况下颅内压升高，脑脊液正常。PTCS可能是原发的，也称为特发性颅内高压（IIH），或继发于可识别的原因，如阻塞性睡眠呼吸暂停（OSA）。原发性和继发性PTCS具有相似的临床特征。病例介绍：我们报告一例43岁女性，体重正常，最初怀疑为IIH，随后被诊断为由舌根肿瘤引起的继发性PTCS，导致OSA。她的症状与PTCS一致，包括头痛、短暂性视力模糊和进行性视力下降。眼底镜检查显示双侧严重乳头水肿，腰椎穿刺显示开口压力43 cm H2O。尽管用乙酰唑胺治疗，她的视力恶化，视神经鞘开窗。进一步的调查发现，由舌头良性肿瘤引起的阻塞性睡眠呼吸暂停是潜在的病因。持续气道正压治疗后，头痛和乳头水肿消失。结论：该病例说明了在诊断为PTCS的患者中彻底寻找继发原因的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Neurology Medicine-Neurology (clinical)

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： This new peer-reviewed online-only journal publishes original case reports covering the entire spectrum of neurology. Clinicians and researchers are given a tool to disseminate their personal experience to a wider public as well as to review interesting cases encountered by colleagues all over the world. To complement the contributions supplementary material is welcomed. The reports are searchable according to the key words supplied by the authors; it will thus be possible to search across the entire growing collection of case reports with universally used terms, further facilitating the retrieval of specific information. Following the open access principle, the entire contents can be retrieved at no charge, guaranteeing easy access to this valuable source of anecdotal information at all times.