Geospatial surveillance of the rabies virus in cattle in Brazil

IF 1.8 3区农林科学 Q1 VETERINARY SCIENCES

Research in veterinary science Pub Date : 2026-05-01 Epub Date: 2026-02-09 DOI:10.1016/j.rvsc.2026.106103

Valdir Vieira da Silva , Denny Parente de Sá Barreto Maia Leite , Pollyanne Raysa Fernandes de Oliveira , Lucilene Martins Trindade Gonçalves , Guilherme Valeriano Silva , Ana Clara Neves dos Santos , Raissa Santana Renovato , Yasmim Victória Santos Pereira , Rafaela Silva Santos , Beatriz Maria de Almeida Braz , Jonatas Campos de Almeida , Rinaldo Aparecido Mota

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引用次数: 0

Abstract

In Brazil, bovine rabies causes significant economic losses and poses a risk to both human and veterinary public health. Its persistence is associated with agricultural expansion, environmental factors, and the presence of reservoirs that favor viral circulation. In this context, spatiotemporal analyses are essential to identify high-risk areas and guide effective surveillance strategies. This study aimed to analyze the spatiotemporal, and temporal trends of bovine rabies in Brazil between 2015 and 2024. An ecological study was conducted using data from the National Animal Health Information System (SIZ), applying spatiotemporal, and temporal trend analyses. A total of 7458 cases were reported during the study period, with higher concentrations in the Southeast (28.26%), South (27.76%), and Central-West (21.99%) regions. The highest incidence risks were observed in the South (8.15/100,000), Southeast (5.69/100,000), and Northeast (2.73/100,000). At the state level, Amapá (81.04/100,000), Paraná (8.51/100,000), Pernambuco (8.41/100,000), Amazonas (8.24/100,000), and São Paulo (7.83/100,000) stood out. Desmodus rotundus plays a central role in the maintenance and transmission of rabies virus to herbivores in Brazil, with case density and records of this species overlapping mainly in Minas Gerais, São Paulo, and Paraná, particularly in areas of pasture, temporary crops, and environmental mosaics. Retrospective analysis identified eight high-risk spatiotemporal clusters, with the primary cluster located in the South and Southeast (2015–2019), showing a relative risk (RR) of 2.86. Prospective analysis revealed five recent clusters, with the primary one located in Paraná and Santa Catarina (2022–2024; RR = 3.88). Joinpoint regression demonstrated an overall decreasing trend in incidence risk (APC: −8.6%). This is the first nationwide study integrating spatiotemporal, and temporal analyses of bovine rabies, highlighting its widespread occurrence across Brazil and identifying strategic areas for strengthening control measures.

Keywords

Bovine rabies

Spatiotemporal analysis

Epidemiology

Risk clusters

Brazil

Abstract Image

查看原文本刊更多论文

巴西牛狂犬病毒的地理空间监测。

在巴西，牛狂犬病造成重大经济损失，并对人类和兽医公共卫生构成风险。它的持续存在与农业扩张、环境因素和有利于病毒循环的水库的存在有关。在这种情况下，时空分析对于确定高风险地区和指导有效的监测战略至关重要。本研究旨在分析2015 - 2024年巴西牛狂犬病的时空和时间趋势。利用国家动物卫生信息系统（SIZ）的数据，应用时空和时间趋势分析进行了生态研究。研究期间共报告病例7458例，集中在东南部（28.26%）、南部（27.76%）和中西部（21.99%）地区。南部（8.15/10万）、东南部（5.69/10万）和东北部（2.73/10万）的发病风险最高。在州一级，amapap（81.04/10万）、paranar（8.51/10万）、Pernambuco（8.41/10万）、Amazonas（8.24/10万）和 o Paulo（7.83/10万）脱颖而出。在巴西，圆形棘球绦虫在狂犬病病毒维持和向食草动物传播方面发挥着核心作用，该物种的病例密度和记录主要在米纳斯吉拉斯州、圣保罗州和帕拉纳岛重叠，特别是在牧场、临时作物和环境马赛克地区。回顾性分析确定了8个高风险时空集群，主要集群位于南部和东南部（2015-2019），相对风险（RR）为2.86。前瞻性分析显示最近有5个集群，主要位于帕拉纳和圣卡塔琳娜（2022-2024;RR = 3.88）。联合点回归显示总体发病率风险呈下降趋势（APC: -8.6%）。这是首个整合牛狂犬病时空和时间分析的全国性研究，突出了其在巴西各地的广泛发生，并确定了加强控制措施的战略领域。关键词：牛狂犬病；时空分析；流行病学；

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Research in veterinary science 农林科学-兽医学

CiteScore

4.40

自引率

4.20%

发文量

312

审稿时长

75 days

期刊介绍： Research in Veterinary Science is an International multi-disciplinary journal publishing original articles, reviews and short communications of a high scientific and ethical standard in all aspects of veterinary and biomedical research. The primary aim of the journal is to inform veterinary and biomedical scientists of significant advances in veterinary and related research through prompt publication and dissemination. Secondly, the journal aims to provide a general multi-disciplinary forum for discussion and debate of news and issues concerning veterinary science. Thirdly, to promote the dissemination of knowledge to a broader range of professions, globally. High quality papers on all species of animals are considered, particularly those considered to be of high scientific importance and originality, and with interdisciplinary interest. The journal encourages papers providing results that have clear implications for understanding disease pathogenesis and for the development of control measures or treatments, as well as those dealing with a comparative biomedical approach, which represents a substantial improvement to animal and human health. Studies without a robust scientific hypothesis or that are preliminary, or of weak originality, as well as negative results, are not appropriate for the journal. Furthermore, observational approaches, case studies or field reports lacking an advancement in general knowledge do not fall within the scope of the journal.