Hypertension in Women Across the Life Cycle: Unique Aspects and Challenges.

IF 6.3 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Current Hypertension Reports Pub Date : 2026-02-20 DOI:10.1007/s11906-026-01362-x

Rachel M Bond, Vikramjit Purewal, Natalie Cameron, Kardie Tobb, Demilade Adedinsewo, Ijeoma Isiadinso, Kameelah Phillips

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引用次数: 0

Abstract

Background: Hypertension is a major driver of cardiovascular morbidity and mortality in women, with risk trajectories that evolve across the female life course. From reproductive years through menopause, sex-specific biological, hormonal, and social factors contribute to unique patterns of blood pressure risk and cardiovascular vulnerability.

Objective: To provide a life-course review of hypertension in adult women and highlight stage-specific risk factors, clinical considerations, and opportunities for prevention and management.

Content: Women experience distinct exposures that influence hypertension risk, including hypertensive disorders of pregnancy, adverse pregnancy outcomes, psychosocial stressors, cardiometabolic changes, and the transition through menopause. This review integrates key recommendations from the 2025 American College of Cardiology/American Heart Association High Blood Pressure Guideline and emphasizes practical, stage-specific approaches to screening, risk stratification, and treatment tailored to women.

Conclusions: A life-stage-specific, sex-informed approach to hypertension is essential to improve early identification, optimize treatment, and reduce long-term cardiovascular risk in women. Addressing persistent evidence gaps and prioritizing implementation of sex-specific care strategies will be critical to advancing equitable cardiovascular outcomes.

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高血压妇女在整个生命周期：独特的方面和挑战。

背景：高血压是女性心血管疾病发病率和死亡率的主要驱动因素，其风险轨迹在整个女性生命过程中不断演变。从生育年龄到更年期，性别特异性的生物、激素和社会因素构成了血压风险和心血管易感性的独特模式。目的：提供成年女性高血压的生命历程回顾，并强调特定阶段的危险因素、临床注意事项以及预防和管理的机会。内容：妇女经历影响高血压风险的不同暴露，包括妊娠期高血压疾病、不良妊娠结局、心理社会压力源、心脏代谢变化和绝经过渡期。本综述整合了2025年美国心脏病学会/美国心脏协会高血压指南的主要建议，并强调了针对女性的筛查、风险分层和治疗的实用、阶段特异性方法。结论：针对女性高血压患者的生命阶段、性别知情的治疗方法对于提高早期识别、优化治疗和降低长期心血管风险至关重要。解决持续存在的证据差距和优先实施针对性别的护理战略对于促进公平的心血管结局至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Hypertension Reports 医学-外周血管病

CiteScore

10.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of hypertension. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as antihypertensive therapies, associated metabolic disorders, and therapeutic trials. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.