[Autism detection based on computational analysis of parental language].

IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Medicina-buenos Aires Pub Date : 2026-03-01
Maria Eleonora Minissi, Alberto Altozano, Lucia Gómez-Zaragozá, Luna Maddalon, Mariano Alcañiz, Javier Marín-Morales
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引用次数: 0

Abstract

Early detection of autism spectrum disorder (ASD) requires integrating clinical observation with developmental history and everyday functioning, yet care pathways are often strained by high demand and limited specialist resources. In this context, parents' narratives provide ecologically valid signals about social communication, language, and repetitive behaviors; however, free-form accounts are difficult to analyze systematically in routine practice. This article reviews a special study, which automatically analyzed caregivers' openended responses to 12 questions inspired by the ADI-R in 51 families (children aged 2-8 years; 25 ASD and 26 controls). The study aimed to automatically detect ASD in children through computational analysis of parents' speech. The best subject-level classification strategy was achieved by converting text into semantic representations (using OpenAI's text-ada-embedding-large-v3), training models per question, including the question in the input, and aggregating decisions via majority voting (84% accuracy; ROC-AUC 1.0). The clinical goal of this pilot study was to demonstrate the potential to support screening, prioritization, and referral, and potentially reduce waiting times and professional burden, thereby improving timely access to evaluation and early intervention. We discuss limitations (small sample, selected population, possible influence of prior intervention) and ethical risks (sociolinguistic bias, privacy, stigmatization, false positives/negatives), and we propose steps toward responsible clinical translation.

[基于父母语言计算分析的自闭症检测]。
自闭症谱系障碍(ASD)的早期检测需要将临床观察与发育历史和日常功能相结合,但由于需求高和专科资源有限,护理途径往往紧张。在这种情况下,父母的叙述提供了关于社会沟通、语言和重复行为的生态有效信号;然而,在日常实践中,对自由格式会计进行系统分析是困难的。本文回顾了一项特殊的研究,该研究自动分析了51个家庭(2-8岁儿童,25名ASD和26名对照)中看护者对由ADI-R激发的12个问题的开放式回答。该研究旨在通过对父母言语的计算分析来自动检测儿童的自闭症。通过将文本转换为语义表示(使用OpenAI的text-ada- embedt-large -v3),每个问题的训练模型,包括输入中的问题,以及通过多数投票聚合决策(准确率84%;ROC-AUC 1.0),可以实现最佳主题级分类策略。该试点研究的临床目标是证明支持筛查、优先排序和转诊的潜力,并可能减少等待时间和专业负担,从而改善及时获得评估和早期干预的机会。我们讨论了局限性(小样本、精选人群、先前干预的可能影响)和伦理风险(社会语言学偏见、隐私、污名化、假阳性/阴性),并提出了实现负责任临床翻译的步骤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medicina-buenos Aires
Medicina-buenos Aires 医学-医学:内科
CiteScore
1.30
自引率
12.50%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Information not localized
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