[Factors associated with ADHD medication adherence and treatment outcomes].

IF 0.6 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Medicina-buenos Aires Pub Date : 2026-03-01

Hali Temkin, Kerri L Daniel, Diana Martinez, Julia C Bennett, Paris A Nix, Linh Nguyen, Yen-Chi Le, Bruno Kluwe-Schiavon, Cesar A Soutullo

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引用次数: 0

Abstract

Introduction: Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that affects 5 to 8% of youth and 2.5 to 4% of adults. Pharmacological treatments are among the most effective when treating ADHD, yet adherence to medication is still sub-optimal. We reviewed the literature on clinical and socio demographic factors that may influence adherence and compared it to our clinical data.

Methods: We conducted a targeted literature review on factors associated with ADHD medication adherence. These factors were compared within our sample of patients aged 3-18 with ADHD at the Child and Adolescent Mood Disorders Program (ChAMP) at (UT Health) - Houston. We assessed relations between measurement-based care (MBC) and socio demographic factors.

Results: We found factors associated with adherence rates included patient age, level of parental involvement, psychiatric comorbidities, familial psychiatric history, and socioeconomic status. ADHD medication adherence improved and symptom severity decreased over 24 months. Each additional year in age, multiple siblings, and =1 parent receiving psychiatric treatment were associated with greater symptom severity.

Discussion: Results suggest that MBC is a useful method for reducing overall ADHD severity and improving medication adherence in children and adolescents. Additionally, MBC programs should consider screening for and addressing family psychiatric history and household structure as these relevant factors affect ADHD medication adherence.

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[与ADHD药物依从性和治疗结果相关的因素]。

简介：注意力缺陷/多动障碍（ADHD）是一种神经发育障碍，影响5 - 8%的青少年和2.5 - 4%的成年人。药物治疗是治疗多动症最有效的方法之一，但坚持服药仍然是次优的。我们回顾了可能影响依从性的临床和社会人口因素的文献，并将其与我们的临床数据进行了比较。方法：我们对ADHD药物依从性相关因素进行了有针对性的文献综述。这些因素在休斯敦（UT Health）儿童和青少年情绪障碍项目（ChAMP）的3-18岁ADHD患者样本中进行了比较。我们评估了基于测量的护理（MBC）与社会人口因素之间的关系。结果：我们发现与依从率相关的因素包括患者年龄、父母参与程度、精神合并症、家族精神病史和社会经济地位。24个月后，ADHD药物依从性改善，症状严重程度下降。年龄每增加一岁，接受精神治疗的多个兄弟姐妹和父母中有1人与更严重的症状相关。讨论：结果表明，MBC是降低儿童和青少年ADHD总体严重程度和提高药物依从性的有效方法。此外，MBC节目应考虑筛查和处理家庭精神病史和家庭结构，因为这些相关因素会影响ADHD药物依从性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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