Practice-Based Consensus Amongst Indian Neurologists: Adopting Remote Electrical Neuromodulation for Effective Management of Migraine

IF 4 3区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

Advances in Therapy Pub Date : 2026-02-16 DOI:10.1007/s12325-026-03500-y

Debashish Chowdhury, Jaydip Ray Chaudhuri, Pravar Passi, Rajasekar Reddi, Rajiv Anand, Sumit Singh, T. K. Banerjee, Vikram Sharma, Mayank Ravindra Dhore, Sujeet Narayan Charugulla, Bhavesh P. Kotak, Sukhpreet Singh

{"title":"Practice-Based Consensus Amongst Indian Neurologists: Adopting Remote Electrical Neuromodulation for Effective Management of Migraine","authors":"Debashish Chowdhury, Jaydip Ray Chaudhuri, Pravar Passi, Rajasekar Reddi, Rajiv Anand, Sumit Singh, T. K. Banerjee, Vikram Sharma, Mayank Ravindra Dhore, Sujeet Narayan Charugulla, Bhavesh P. Kotak, Sukhpreet Singh","doi":"10.1007/s12325-026-03500-y","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Migraine is a major cause of disability in India, disproportionately affecting women and adolescents. Although traditional pharmacological treatments exist, side effects and poor adherence have increased interest in non-pharmacological options such as remote electrical neuromodulation (REN). However, clinical adoption of REN remains limited because of the absence of clear, India-specific guidelines.</p><h3>Methods</h3><p>An Indian consensus was developed through a two-phase Delphi process involving 49 neurologists. Phase 1 included a scientific committee of eight neurologists who conducted a targeted literature review on REN and formulated 27 consensus statements. In phase 2, 41 neurologists from across India participated in modified Delphi rounds to finalize these statements.</p><h3>Results</h3><p>Statements achieving over 60% agreement identified REN as a promising and well-tolerated non-pharmacological therapy that addresses limitations of current migraine treatments. High consensus (75–97.22%) highlighted REN’s favorable safety profile, minimal adverse events, and suitability for adolescents and women of childbearing age.</p><h3>Conclusion</h3><p>This Indian consensus provides practical guidance for integrating REN into migraine management. The REN device shows potential as a first-line or adjunct therapy, particularly for patients facing challenges with pharmacological treatment adherence, supporting its wider adoption in clinical practice.</p></div>","PeriodicalId":7482,"journal":{"name":"Advances in Therapy","volume":"43 4","pages":"1622 - 1638"},"PeriodicalIF":4.0000,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s12325-026-03500-y.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Therapy","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s12325-026-03500-y","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction

Migraine is a major cause of disability in India, disproportionately affecting women and adolescents. Although traditional pharmacological treatments exist, side effects and poor adherence have increased interest in non-pharmacological options such as remote electrical neuromodulation (REN). However, clinical adoption of REN remains limited because of the absence of clear, India-specific guidelines.

Methods

An Indian consensus was developed through a two-phase Delphi process involving 49 neurologists. Phase 1 included a scientific committee of eight neurologists who conducted a targeted literature review on REN and formulated 27 consensus statements. In phase 2, 41 neurologists from across India participated in modified Delphi rounds to finalize these statements.

Results

Statements achieving over 60% agreement identified REN as a promising and well-tolerated non-pharmacological therapy that addresses limitations of current migraine treatments. High consensus (75–97.22%) highlighted REN’s favorable safety profile, minimal adverse events, and suitability for adolescents and women of childbearing age.

Conclusion

This Indian consensus provides practical guidance for integrating REN into migraine management. The REN device shows potential as a first-line or adjunct therapy, particularly for patients facing challenges with pharmacological treatment adherence, supporting its wider adoption in clinical practice.

查看原文本刊更多论文

基于实践的共识在印度神经科医生：采用远程电神经调节偏头痛的有效管理。

在印度，偏头痛是导致残疾的一个主要原因，对妇女和青少年的影响尤为严重。虽然存在传统的药物治疗，但副作用和不良依从性增加了对非药物选择的兴趣，如远程电神经调节（REN）。然而，由于缺乏明确的、针对印度的指导方针，REN的临床应用仍然有限。方法：通过涉及49名神经科医生的两阶段德尔菲过程，形成印度共识。第一阶段包括一个由8名神经学家组成的科学委员会，他们对REN进行了有针对性的文献回顾，并制定了27项共识声明。在第二阶段，来自印度各地的41名神经科医生参加了修改后的德尔菲轮次，以最终确定这些陈述。结果：超过60%的声明一致认为REN是一种有前景且耐受性良好的非药物治疗方法，解决了当前偏头痛治疗的局限性。高共识（75-97.22%）强调了REN良好的安全性，最小的不良事件，适合青少年和育龄妇女。结论：这一印度共识为将REN纳入偏头痛治疗提供了实用指导。REN装置显示出作为一线或辅助治疗的潜力，特别是对于面临药物治疗依从性挑战的患者，支持其在临床实践中的广泛采用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Advances in Therapy 医学-药学

CiteScore

7.20

自引率

2.60%

发文量

353

审稿时长

6-12 weeks

期刊介绍： Advances in Therapy is an international, peer reviewed, rapid-publication (peer review in 2 weeks, published 3–4 weeks from acceptance) journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of therapeutics and interventions (including devices) across all therapeutic areas. Studies relating to diagnostics and diagnosis, pharmacoeconomics, public health, epidemiology, quality of life, and patient care, management, and education are also encouraged. The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Advances in Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.