Global burden of rheumatic heart disease among women of reproductive age: Socioeconomic and temporal trends, 1990 to 2021

IF 2.9 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases Pub Date : 2026-08-01 Epub Date: 2026-01-23 DOI:10.1016/j.acvd.2026.01.003

Ran Li, Shuxiao Hou, Junhui Wu

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引用次数: 0

Abstract

Background

Women of reproductive age are an important group to consider in the global burden of rheumatic heart disease (RHD).

Aim

We aimed to systematically analyse the burden of RHD among women of reproductive age from 1990 to 2021.

Methods

We used Global Burden of Disease (GBD) 2021 to comprehensively analyse the global burden of RHD among women of reproductive age, including incidence, prevalence, mortality and disability-adjusted life years (DALY) and examined the relationship between the burden of disease and different regions, sociodemographic index (SDI) and age.

Results

The incidence and prevalence rates of RHD in women of reproductive age increased globally from 1990 to 2021. The incidence rate (per 100,000 population) increased from 60.37 (95% UI: 44.12–82.42) in 1990 to 64.06 (95% UI: 46.24–86.76) in 2021 and the prevalence rate increased from 951.74 (95% UI: 723.08–1197.48) to 1110.17 (95% UI: 843.45–1402.27). When countries were grouped by SDI, incidence rate and prevalence rate negatively correlated with SDI. Low SDI regions had the highest burden. In 2021, women of reproductive age 15–19 years had the most incident cases, and the number of deaths and DALY connected positively with age.

Conclusions

The increasing incidence of RHD among women of reproductive age represents an important global health concern, particularly in low-SDI regions where the disease burden remains highest. The early onset of RHD highlights the need for preventive efforts targeting younger women. Prevention and management strategies should be adapted to disease patterns and health-system capacity, with an emphasis on early detection and effective secondary prevention in high-burden settings.

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育龄妇女风湿性心脏病的全球负担：1990年至2021年的社会经济和时间趋势

背景：育龄妇女是风湿性心脏病（RHD）全球负担中需要考虑的重要群体。目的：我们旨在系统地分析1990年至2021年育龄妇女的RHD负担。方法：采用全球疾病负担（GBD） 2021，综合分析育龄妇女RHD的全球负担，包括发病率、患病率、死亡率和残疾调整生命年（DALY），并探讨疾病负担与不同地区、社会人口指数（SDI）和年龄的关系。结果：从1990年到2021年，全球育龄妇女RHD的发病率和患病率呈上升趋势。发病率（每10万人）从1990年的60.37例（95% UI: 44.12-82.42）上升到2021年的64.06例（95% UI: 46.24-86.76），患病率从951.74例（95% UI: 723.08-1197.48）上升到1110.17例（95% UI: 843.45-1402.27）。当按SDI分组时，发病率和患病率与SDI呈负相关。低SDI地区的负担最高。2021年，15-19岁育龄妇女的发病率最高，死亡人数和伤残调整寿命与年龄呈正相关。结论：育龄妇女RHD发病率的增加是一个重要的全球健康问题，特别是在疾病负担仍然最高的低sdi地区。RHD的早期发病突出了针对年轻女性进行预防工作的必要性。预防和管理战略应适应疾病模式和卫生系统的能力，重点是在高负担环境中早期发现和有效的二级预防。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Cardiovascular Diseases 医学-心血管系统

CiteScore

4.40

自引率

6.70%

发文量

审稿时长

34 days

期刊介绍： The Journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles and editorials. Topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.