{"title":"Enhanced Detection of Diabetic Retinopathy using GAI-Net: Deep Learning Model based on GAN with Autoencoder","authors":"Chilukuri Rajitha, P Praveen, K Rajchandar","doi":"10.1016/j.asej.2026.104050","DOIUrl":null,"url":null,"abstract":"<div><div>Diabetic Retinopathy (DR) is a serious illness associated with diabetes and is one of the leading causes of universal visual impairment. Early and proper diagnosis is crucial to prevent permanent eye damage. The proposed paper introduces a new hybrid deep learning framework, GAI-Net, that uses Generative Adversarial Networks (GANs), Autoencoders, and InceptionV3 to detect DR in five levels of severity. The model addressed multiple issues in DR detection, including small datasets and class imbalance, through quality synthetic images and discriminative hierarchical features. Generative component increases data variation, and the discriminative modules increases the representation of the features and accuracy in recognition. To compare the performance of the proposed GAI-Net, a comparative analysis was undertaken with advanced models, including traditional GANs, DCGAN, Attention-GAN, EfficientNet GAN, and InceptionV3 through the use of Kaggle dataset images are included. The obtained results indicate that GAI-Net outperforms all other comparative models, achieving a detection accuracy of 0.99 and an F1-score of 0.98, which is a high level of effectiveness. The methodology shows the strengths of combining the generative and discriminative deep learning methods in medical image analysis. GAI-Net is able to diagnose diabetic retinopathy with a scalable, accurate, and entirely automatic model by constructing balanced datasets and improving the encoding of features. The current research paper explains the potential use of hybrid architectures in computer-aided diagnosis, as it helps strengthen the development of the next-generation tools to find diabetic retinopathy with extensive medical uses.</div></div>","PeriodicalId":48648,"journal":{"name":"Ain Shams Engineering Journal","volume":"17 3","pages":"Article 104050"},"PeriodicalIF":6.2000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ain Shams Engineering Journal","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2090447926000778","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/2/14 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"ENGINEERING, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Diabetic Retinopathy (DR) is a serious illness associated with diabetes and is one of the leading causes of universal visual impairment. Early and proper diagnosis is crucial to prevent permanent eye damage. The proposed paper introduces a new hybrid deep learning framework, GAI-Net, that uses Generative Adversarial Networks (GANs), Autoencoders, and InceptionV3 to detect DR in five levels of severity. The model addressed multiple issues in DR detection, including small datasets and class imbalance, through quality synthetic images and discriminative hierarchical features. Generative component increases data variation, and the discriminative modules increases the representation of the features and accuracy in recognition. To compare the performance of the proposed GAI-Net, a comparative analysis was undertaken with advanced models, including traditional GANs, DCGAN, Attention-GAN, EfficientNet GAN, and InceptionV3 through the use of Kaggle dataset images are included. The obtained results indicate that GAI-Net outperforms all other comparative models, achieving a detection accuracy of 0.99 and an F1-score of 0.98, which is a high level of effectiveness. The methodology shows the strengths of combining the generative and discriminative deep learning methods in medical image analysis. GAI-Net is able to diagnose diabetic retinopathy with a scalable, accurate, and entirely automatic model by constructing balanced datasets and improving the encoding of features. The current research paper explains the potential use of hybrid architectures in computer-aided diagnosis, as it helps strengthen the development of the next-generation tools to find diabetic retinopathy with extensive medical uses.
期刊介绍:
in Shams Engineering Journal is an international journal devoted to publication of peer reviewed original high-quality research papers and review papers in both traditional topics and those of emerging science and technology. Areas of both theoretical and fundamental interest as well as those concerning industrial applications, emerging instrumental techniques and those which have some practical application to an aspect of human endeavor, such as the preservation of the environment, health, waste disposal are welcome. The overall focus is on original and rigorous scientific research results which have generic significance.
Ain Shams Engineering Journal focuses upon aspects of mechanical engineering, electrical engineering, civil engineering, chemical engineering, petroleum engineering, environmental engineering, architectural and urban planning engineering. Papers in which knowledge from other disciplines is integrated with engineering are especially welcome like nanotechnology, material sciences, and computational methods as well as applied basic sciences: engineering mathematics, physics and chemistry.