Visible-light-promoted regioselective C5–H selenylation of pyrrolo[2,3-d] pyrimidine derivatives with diorganyldiselenides

IF 2.2 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2026-06-01 Epub Date: 2026-02-06 DOI:10.1016/j.tet.2026.135175

Zixuan Liu , Mingrui Liu , Yaorong Liu, Jiaqi Tong, Xingxian Zhang

引用次数: 0

Abstract

A metal-free photochemical methodology has been developed for the direct C–H selenylation of pyrrolo[2,3-d]pyrimidines. The protocol features broad substrate scope, operational simplicity, mild reaction conditions, and utilizes safe and readily available diphenyl diselenide as the selenium source. This methodology is also applicable for selenylation of certain heteroarenes. Stern–Volmer experiments have indicated that photo-excited Na₂-eosinY∗ is effectively quenched and linearly correlated with the concentration of diphenyl diselenide.

Abstract Image

查看原文本刊更多论文

可见光促进吡咯[2,3-d]嘧啶衍生物与二有机基二硒化物的C5-H选择性硒化反应

一种无金属的光化学方法已经开发用于直接C-H硒化吡咯[2,3-d]嘧啶。该方案具有底物范围广，操作简单，反应条件温和，并使用安全且易于获得的二苯二烯作为硒源的特点。这种方法也适用于某些杂芳烃的硒化反应。Stern-Volmer实验表明，光激发的na2 -eosin *被有效猝灭，并与二苯二烯的浓度呈线性相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.