Management of Behavioral and Psychological Symptoms of Dementia: Nonpharmacologic and Pharmacologic Interventions.

IF 16.5 1区心理学 Q1 PSYCHOLOGY

Annual Review of Clinical Psychology Pub Date : 2026-05-01 Epub Date: 2026-02-12 DOI:10.1146/annurev-clinpsy-061724-085912

Jennifer A Watt, Zahinoor Ismail, Natasha Lane, Dallas Seitz, Zahra Goodarzi

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引用次数: 0

Abstract

Mounting evidence supports the efficacy of nonpharmacologic or psychosocial interventions for reducing behavioral and psychological symptoms of dementia (BPSD), identifies the comparative risks and benefits of psychotropic medication, and underscores the importance of deprescribing psychotropic medications. However, evidence from clinical settings indicates that uptake of nonpharmacologic interventions and potential overuse of medications remain problematic. We begin by discussing the importance of exploring potential contributors to BPSD, using person-centered language to describe BPSD, implementing holistic and person-centered care plans, measuring clinically important changes in BPSD, and considering social determinants of health when assessing and managing BPSD; we also discuss the historical context informing how clinicians manage BPSD. Next, we compare and contrast nonpharmacologic and pharmacologic approaches to managing BPSD, evaluate their individual and comparative efficacy, and describe recommendations for intervention deprescribing or deimplementation. Lastly, we discuss strengths and limitations of the current evidence supporting BPSD management as well as recommendations for future research.

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痴呆的行为和心理症状的管理：非药物和药物干预。

越来越多的证据支持非药物或社会心理干预对减少痴呆症的行为和心理症状（BPSD）的有效性，确定了精神药物的相对风险和益处，并强调了精神药物处方的重要性。然而，来自临床环境的证据表明，接受非药物干预和潜在的过度使用药物仍然存在问题。我们首先讨论了探索BPSD的潜在贡献者的重要性，使用以人为中心的语言来描述BPSD，实施整体和以人为中心的护理计划，测量BPSD的临床重要变化，以及在评估和管理BPSD时考虑健康的社会决定因素；我们还讨论了历史背景，告知临床医生如何管理BPSD。接下来，我们比较和对比了治疗BPSD的非药物和药物方法，评估了它们的个体和比较疗效，并描述了对干预措施的建议。最后，我们讨论了支持BPSD管理的现有证据的优势和局限性，以及对未来研究的建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annual Review of Clinical Psychology 医学-心理学

CiteScore

31.50

自引率

0.50%

发文量

期刊介绍： The Annual Review of Clinical Psychology is a publication that has been available since 2005. It offers comprehensive reviews on significant developments in the field of clinical psychology and psychiatry. The journal covers various aspects including research, theory, and the application of psychological principles to address recognized disorders such as schizophrenia, mood, anxiety, childhood, substance use, cognitive, and personality disorders. Additionally, the articles also touch upon broader issues that cut across the field, such as diagnosis, treatment, social policy, and cross-cultural and legal issues. Recently, the current volume of this journal has transitioned from a gated access model to an open access format through the Annual Reviews' Subscribe to Open program. All articles published in this volume are now available under a Creative Commons Attribution License (CC BY), allowing for widespread distribution and use. The journal is also abstracted and indexed in various databases including Scopus, Science Citation Index Expanded, MEDLINE, EMBASE, CINAHL, PsycINFO, and Academic Search, among others.