[An autopsy case report of combined hepatocellular-cholangiocarcinoma in a young woman without chronic liver disease].

Abstract

This case concerns a woman in her 20s with abdominal pain. Abdominal computed tomography revealed a large hepatic tumor with extensive infiltration of both liver lobes. She developed acute liver failure and was immediately admitted to our hospital. Her condition rapidly deteriorated, progressing to multiple organ failure, leaving insufficient time for comprehensive evaluation. She died 4 days after admission. Autopsy showed marked hepatomegaly due to tumor, with the liver weighing 3400g. Pathological diagnosis was combined hepatocellular-cholangiocarcinoma (cHCC-CCA), a rare primary liver cancer. We report an extremely rare case of cHCC-CCA in a young woman without a history of chronic liver disease.