Ilaria Condò, Marcella Trombetta, Emiliano Schena, Daniela Lo Presti, Sara Maria Giannitelli
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引用次数: 0
Abstract
Wearable sensors that combine high precision with conformability and skin adhesion are crucial for reliable and highly unobtrusive physiological monitoring. In this context, increasing efforts are directed toward next-generation miniaturized self-adhesive sensors employing different sensing technologies. Herein, for the first time a self-adhesive sensor is developed for real-time detection of physiological and biomechanical strain signals, by embedding a fiber Bragg grating (FBG) sensor into a soft, biomimetic, flexible matrix. This hydrogel-based matrix, composed of gelatin methacrylate, xanthan gum, and glycerol, is engineered to balance fiber–matrix mechanical coupling and skin adhesion. The encapsulated FBG sensor exhibits stable optical response, reduced signal attenuation, and retains good sensitivity to both strain (0.07 nm mε−1) and temperature (0.01 nm °C−1). Preliminary on-skin tests on a healthy volunteer demonstrate the ability to capture subtle physiological signals such as breathing and heartbeats, as well as limb motion. Notably, the self-adhesive properties of the matrix enable firm skin contact without additional tapes, enhancing signal reliability, and reducing motion artifacts. This approach offers a robust, biocompatible, and scalable solution for wearable sensing, opening new opportunities in health monitoring, rehabilitation, and human–machine interfaces.
期刊介绍:
Advanced NanoBiomed Research will provide an Open Access home for cutting-edge nanomedicine, bioengineering and biomaterials research aimed at improving human health. The journal will capture a broad spectrum of research from increasingly multi- and interdisciplinary fields of the traditional areas of biomedicine, bioengineering and health-related materials science as well as precision and personalized medicine, drug delivery, and artificial intelligence-driven health science.
The scope of Advanced NanoBiomed Research will cover the following key subject areas:
▪ Nanomedicine and nanotechnology, with applications in drug and gene delivery, diagnostics, theranostics, photothermal and photodynamic therapy and multimodal imaging.
▪ Biomaterials, including hydrogels, 2D materials, biopolymers, composites, biodegradable materials, biohybrids and biomimetics (such as artificial cells, exosomes and extracellular vesicles), as well as all organic and inorganic materials for biomedical applications.
▪ Biointerfaces, such as anti-microbial surfaces and coatings, as well as interfaces for cellular engineering, immunoengineering and 3D cell culture.
▪ Biofabrication including (bio)inks and technologies, towards generation of functional tissues and organs.
▪ Tissue engineering and regenerative medicine, including scaffolds and scaffold-free approaches, for bone, ligament, muscle, skin, neural, cardiac tissue engineering and tissue vascularization.
▪ Devices for healthcare applications, disease modelling and treatment, such as diagnostics, lab-on-a-chip, organs-on-a-chip, bioMEMS, bioelectronics, wearables, actuators, soft robotics, and intelligent drug delivery systems.
with a strong focus on applications of these fields, from bench-to-bedside, for treatment of all diseases and disorders, such as infectious, autoimmune, cardiovascular and metabolic diseases, neurological disorders and cancer; including pharmacology and toxicology studies.