Potential roles of unmeasured spectra and light’s frequency-dependent neural modulation in daylight-mediated metabolic improvements

Abstract

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We read with great interest the recent article by Harmsen et al. demonstrating that natural daylight during office hours improves glucose control and whole-body substrate metabolism in individuals with type 2 diabetes.¹ Harmsen et al.’s work provides valuable insights into the metabolic impacts of indoor lighting environments, but we wish to raise two complementary points that may extend mechanistic understanding and inform future study design considerations.First, the spectral analysis in

Acknowledgments

This study was supported by the National Natural Science Foundation of China (32300959), Guangzhou Scientific Research Grant (SL2024A04J00578), and the SCNU Young Faculty Development Program (22KJ04).

Declaration of interests

The authors declare no competing interests.