{"title":"Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness Analysis in Treatment - Naive Glaucoma Patients.","authors":"Sushil Kumar, Ashok Kumar, Ankita Singh, Bhupesh Bhatkoti, Kumar Vijay Sharma, Vikas Ambiya, Vipin Rana","doi":"10.31348/2026/5","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong> To evaluate RNFL (Retinal Nerve Fiber Layer) and GCC (Ganglion Cell Complex) thickness, using SD-OCT in treatment-naive patients of primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and normal-tension glaucoma (NTG) and to compare these findings with healthy controls.</p><p><strong>Material and methods: </strong> The study included 150 eyes of 75 glaucoma patients (25 each of POAG, PACG, NTG) and 200 eyes of 100 controls. In this cross-sectional observational study, patients meeting the inclusion criteria underwent comprehensive ophthalmic examinations, including best-corrected visual acuity, intraocular pressure (IOP) by Goldmann applanation tonometry (GAT), gonioscopy to differentiate between open and closed angle and visual field analysis (VFA). GCC-IPL and RNFL thickness were measured using SD-OCT.</p><p><strong>Results: </strong> Significant thinning of RNFL was noted in all glaucoma subtypes, especially in inferior and superior quadrants (p.</p>","PeriodicalId":39839,"journal":{"name":"Ceska a Slovenska Oftalmologie","volume":"82 Ahead of Print","pages":"1-7"},"PeriodicalIF":0.0000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ceska a Slovenska Oftalmologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31348/2026/5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: To evaluate RNFL (Retinal Nerve Fiber Layer) and GCC (Ganglion Cell Complex) thickness, using SD-OCT in treatment-naive patients of primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and normal-tension glaucoma (NTG) and to compare these findings with healthy controls.
Material and methods: The study included 150 eyes of 75 glaucoma patients (25 each of POAG, PACG, NTG) and 200 eyes of 100 controls. In this cross-sectional observational study, patients meeting the inclusion criteria underwent comprehensive ophthalmic examinations, including best-corrected visual acuity, intraocular pressure (IOP) by Goldmann applanation tonometry (GAT), gonioscopy to differentiate between open and closed angle and visual field analysis (VFA). GCC-IPL and RNFL thickness were measured using SD-OCT.
Results: Significant thinning of RNFL was noted in all glaucoma subtypes, especially in inferior and superior quadrants (p.
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