Epileptic Seizure Detection from EEG Signals with Long Short-Term Memory-Transformer and Self-Supervised Learning.

Abstract

Electroencephalogram (EEG) plays a vital role in seizure detection, yet existing methods often fail to adequately capture the spatiotemporal characteristics of EEG signals, leading to limited performance. Moreover, most current models depend on supervised learning and thus require large amounts of labeled data. To address these issues, this paper introduces the Long Short-Term Memory-Transformer (LTformer) encoder, designed to model long-term temporal dependencies in EEG signals while retaining spatial information across electrode channels. We further propose a dual-stream self-supervised learning (SSL) strategy to pretrain the model, enabling the LTformer encoder to learn discriminative representations from extensive unlabeled EEG data. After pretext training, the encoder is transferred and fine-tuned for downstream seizure detection. The proposed method, termed Self-Supervised Attention LTformer (SALT), is evaluated on two public EEG datasets using both segment-based and event-based experimental protocols. In the segment-based evaluation, SALT achieves 98.87% sensitivity, 99.15% accuracy, and 99.41% specificity on CHB-MIT, and 98.04% sensitivity, 97.72% accuracy, and 97.62% specificity on Siena. In the event-based evaluation, SALT attains 98.57% sensitivity with a false discovery rate (FDR) of 0.26 on CHB-MIT, and 98.65% sensitivity with an FDR of 0.25 on Siena. The code is publicly available at https://github.com/peutim114/SALT.