Harnessing Genetic Engineering for Petrochemical Waste Detoxification: Mechanisms and Recent Breakthroughs

IF 3.3 4区 生物学 Q2 MICROBIOLOGY
Atul Kumar Srivastava, Gyanendra Tripathi, Vikram Singh,  Ashish, Xin Xie
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引用次数: 0

Abstract

Petrochemicals have emerged as an environmental hazard requiring innovative, sustainable remediation strategies. Bioremediation, specifically by genetically modified microorganisms (GMMs), is well known to produce surfactants that have emerged as a promising source to catalyze the efficiency of hydrocarbon degradation. The surfactant produced by GMMs facilitates the emulsification and dispersion of petroleum hydrocarbons. This review discusses the current state of biodegradation research, specifically on GMMs engineered to synthesize surfactant, which play an important role in enhancing the solubility of hydrophobic contaminants, such as oil components, thereby enhancing microbial access for degradation. The GMMs explored to optimize surfactant production and tailor their bioremediation efficiency. Furthermore, highlights the environmental benefits of utilizing GMMs for surfactant production, emphasizing the potential for a sustainable and cost-effective remediation strategy. Challenges and ethical considerations associated with the release of genetically modified organisms into the environment are also discussed, underscoring the importance of thorough risk assessments and regulatory frameworks. In conclusion, the integration of GMMs capable of producing surfactants presents a promising avenue for addressing petrochemicals through efficient and environmentally conscious bioremediation strategies. Future research should focus on optimizing the performance and safety of these engineered organisms to ensure their successful application in real-world environmental scenarios.

利用基因工程进行石油化工废弃物脱毒:机制与最新突破。
石化产品已经成为一种环境危害,需要创新的、可持续的补救策略。生物修复,特别是通过转基因微生物(GMMs),众所周知可以产生表面活性剂,这些表面活性剂已成为催化碳氢化合物降解效率的有前途的来源。GMMs制备的表面活性剂有利于石油烃的乳化和分散。本文综述了生物降解的研究现状,特别是合成表面活性剂的转基因小麦,它在提高疏水污染物(如油成分)的溶解度,从而增加微生物降解的途径方面起着重要作用。GMMs探索了优化表面活性剂产量和调整其生物修复效率的方法。此外,强调了利用转基因生物生产表面活性剂的环境效益,强调了可持续和具有成本效益的补救策略的潜力。还讨论了与将转基因生物释放到环境中相关的挑战和伦理考虑,强调了全面风险评估和监管框架的重要性。综上所述,能够生产表面活性剂的gmm的整合为通过高效和环保的生物修复策略解决石化问题提供了一条有前途的途径。未来的研究应集中于优化这些工程生物的性能和安全性,以确保它们在现实环境中的成功应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Basic Microbiology
Journal of Basic Microbiology 生物-微生物学
CiteScore
6.10
自引率
0.00%
发文量
134
审稿时长
1.8 months
期刊介绍: The Journal of Basic Microbiology (JBM) publishes primary research papers on both procaryotic and eucaryotic microorganisms, including bacteria, archaea, fungi, algae, protozoans, phages, viruses, viroids and prions. Papers published deal with: microbial interactions (pathogenic, mutualistic, environmental), ecology, physiology, genetics and cell biology/development, new methodologies, i.e., new imaging technologies (e.g. video-fluorescence microscopy, modern TEM applications) novel molecular biology methods (e.g. PCR-based gene targeting or cassettes for cloning of GFP constructs).
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