{"title":"Gait recovery after total hip arthroplasty: insights from principal component analysis of pre- and post-surgical walking performance","authors":"Arunee Promsri , Inge Werner , Peter Federolf","doi":"10.1016/j.jbiomech.2026.113173","DOIUrl":null,"url":null,"abstract":"<div><div>Total hip arthroplasty (THA) alleviates pain and restores function in hip osteoarthritis, yet gait abnormalities may persist. We tested two hypotheses: (H1) THA patients would improve from preoperative (M0) to six months postoperative (M6) in principal component analysis (PCA)–derived gait outcomes; (H2) despite improvement, patients at M6 would still differ from healthy adults. Full-body overground kinematics from 50 THA patients (64.9 ± 9.9 years) and 50 healthy adults (64.5 ± 8.9 years) were decomposed using PCA into coordinated movement components (“principal movements,” PMs). Each PM was quantified by the relative explained variance (rVAR; structural contribution), the number of zero-crossings of PM accelerations (N; control reversals/smoothness), and the root-mean-square of PM accelerations (RMS; acceleration magnitude). The first five PMs (PM<sub>1–5</sub>) mapped to recognizable phases: PM<sub>1</sub>—forward progression/propulsion; PM<sub>2</sub>—swing-phase movement; PM<sub>3</sub>—single-leg support with mediolateral stabilization; PM<sub>4</sub>—single-leg support with trunk rotation; PM<sub>5</sub>—double-support transition. Consistent with H1, from M0 to M6 patients showed increased PM<sub>2</sub> rVAR (<em>p</em> = 0.005), reduced N across all PMs (all <em>p</em> ≤ 0.003), and reduced RMS in PM<sub>3–5</sub> (<em>p</em> ≤ 0.001). Consistent with H2, at M6 patients still exhibited a trend in higher rVAR (unadjusted <em>p</em> = 0.022; not significant after multiplicity control) and significantly higher RMS (<em>p</em> = 0.002) in PM<sub>3</sub> versus healthy adults. These findings indicate that THA yields substantial gains over six months—particularly in swing-phase structure and overall smoothness—yet phase-specific deviations persist during single-leg support (mediolateral stabilization), highlighting targets for extended rehabilitation to improve walking performance.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"197 ","pages":"Article 113173"},"PeriodicalIF":2.9000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomechanics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0021929026000278","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/29 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"BIOPHYSICS","Score":null,"Total":0}
引用次数: 0
Abstract
Total hip arthroplasty (THA) alleviates pain and restores function in hip osteoarthritis, yet gait abnormalities may persist. We tested two hypotheses: (H1) THA patients would improve from preoperative (M0) to six months postoperative (M6) in principal component analysis (PCA)–derived gait outcomes; (H2) despite improvement, patients at M6 would still differ from healthy adults. Full-body overground kinematics from 50 THA patients (64.9 ± 9.9 years) and 50 healthy adults (64.5 ± 8.9 years) were decomposed using PCA into coordinated movement components (“principal movements,” PMs). Each PM was quantified by the relative explained variance (rVAR; structural contribution), the number of zero-crossings of PM accelerations (N; control reversals/smoothness), and the root-mean-square of PM accelerations (RMS; acceleration magnitude). The first five PMs (PM1–5) mapped to recognizable phases: PM1—forward progression/propulsion; PM2—swing-phase movement; PM3—single-leg support with mediolateral stabilization; PM4—single-leg support with trunk rotation; PM5—double-support transition. Consistent with H1, from M0 to M6 patients showed increased PM2 rVAR (p = 0.005), reduced N across all PMs (all p ≤ 0.003), and reduced RMS in PM3–5 (p ≤ 0.001). Consistent with H2, at M6 patients still exhibited a trend in higher rVAR (unadjusted p = 0.022; not significant after multiplicity control) and significantly higher RMS (p = 0.002) in PM3 versus healthy adults. These findings indicate that THA yields substantial gains over six months—particularly in swing-phase structure and overall smoothness—yet phase-specific deviations persist during single-leg support (mediolateral stabilization), highlighting targets for extended rehabilitation to improve walking performance.
期刊介绍:
The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership.
Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to:
-Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells.
-Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions.
-Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response.
-Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing.
-Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine.
-Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction.
-Molecular Biomechanics - Mechanical analyses of biomolecules.
-Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints.
-Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics.
-Sports Biomechanics - Mechanical analyses of sports performance.