Gait recovery after total hip arthroplasty: insights from principal component analysis of pre- and post-surgical walking performance

IF 2.9 3区 医学 Q3 BIOPHYSICS
Journal of biomechanics Pub Date : 2026-03-01 Epub Date: 2026-01-29 DOI:10.1016/j.jbiomech.2026.113173
Arunee Promsri , Inge Werner , Peter Federolf
{"title":"Gait recovery after total hip arthroplasty: insights from principal component analysis of pre- and post-surgical walking performance","authors":"Arunee Promsri ,&nbsp;Inge Werner ,&nbsp;Peter Federolf","doi":"10.1016/j.jbiomech.2026.113173","DOIUrl":null,"url":null,"abstract":"<div><div>Total hip arthroplasty (THA) alleviates pain and restores function in hip osteoarthritis, yet gait abnormalities may persist. We tested two hypotheses: (H1) THA patients would improve from preoperative (M0) to six months postoperative (M6) in principal component analysis (PCA)–derived gait outcomes; (H2) despite improvement, patients at M6 would still differ from healthy adults. Full-body overground kinematics from 50 THA patients (64.9 ± 9.9 years) and 50 healthy adults (64.5 ± 8.9 years) were decomposed using PCA into coordinated movement components (“principal movements,” PMs). Each PM was quantified by the relative explained variance (rVAR; structural contribution), the number of zero-crossings of PM accelerations (N; control reversals/smoothness), and the root-mean-square of PM accelerations (RMS; acceleration magnitude). The first five PMs (PM<sub>1–5</sub>) mapped to recognizable phases: PM<sub>1</sub>—forward progression/propulsion; PM<sub>2</sub>—swing-phase movement; PM<sub>3</sub>—single-leg support with mediolateral stabilization; PM<sub>4</sub>—single-leg support with trunk rotation; PM<sub>5</sub>—double-support transition. Consistent with H1, from M0 to M6 patients showed increased PM<sub>2</sub> rVAR (<em>p</em> = 0.005), reduced N across all PMs (all <em>p</em> ≤ 0.003), and reduced RMS in PM<sub>3–5</sub> (<em>p</em> ≤ 0.001). Consistent with H2, at M6 patients still exhibited a trend in higher rVAR (unadjusted <em>p</em> = 0.022; not significant after multiplicity control) and significantly higher RMS (<em>p</em> = 0.002) in PM<sub>3</sub> versus healthy adults. These findings indicate that THA yields substantial gains over six months—particularly in swing-phase structure and overall smoothness—yet phase-specific deviations persist during single-leg support (mediolateral stabilization), highlighting targets for extended rehabilitation to improve walking performance.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"197 ","pages":"Article 113173"},"PeriodicalIF":2.9000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomechanics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0021929026000278","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/29 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"BIOPHYSICS","Score":null,"Total":0}
引用次数: 0

Abstract

Total hip arthroplasty (THA) alleviates pain and restores function in hip osteoarthritis, yet gait abnormalities may persist. We tested two hypotheses: (H1) THA patients would improve from preoperative (M0) to six months postoperative (M6) in principal component analysis (PCA)–derived gait outcomes; (H2) despite improvement, patients at M6 would still differ from healthy adults. Full-body overground kinematics from 50 THA patients (64.9 ± 9.9 years) and 50 healthy adults (64.5 ± 8.9 years) were decomposed using PCA into coordinated movement components (“principal movements,” PMs). Each PM was quantified by the relative explained variance (rVAR; structural contribution), the number of zero-crossings of PM accelerations (N; control reversals/smoothness), and the root-mean-square of PM accelerations (RMS; acceleration magnitude). The first five PMs (PM1–5) mapped to recognizable phases: PM1—forward progression/propulsion; PM2—swing-phase movement; PM3—single-leg support with mediolateral stabilization; PM4—single-leg support with trunk rotation; PM5—double-support transition. Consistent with H1, from M0 to M6 patients showed increased PM2 rVAR (p = 0.005), reduced N across all PMs (all p ≤ 0.003), and reduced RMS in PM3–5 (p ≤ 0.001). Consistent with H2, at M6 patients still exhibited a trend in higher rVAR (unadjusted p = 0.022; not significant after multiplicity control) and significantly higher RMS (p = 0.002) in PM3 versus healthy adults. These findings indicate that THA yields substantial gains over six months—particularly in swing-phase structure and overall smoothness—yet phase-specific deviations persist during single-leg support (mediolateral stabilization), highlighting targets for extended rehabilitation to improve walking performance.
全髋关节置换术后步态恢复:来自术前和术后行走表现的主成分分析的见解。
全髋关节置换术(THA)减轻疼痛和恢复髋关节骨关节炎的功能,但步态异常可能持续存在。我们检验了两个假设:(H1) THA患者在主成分分析(PCA)衍生的步态结果中,从术前(M0)到术后6个月(M6)会有所改善;(H2)尽管有所改善,但M6患者仍与健康成人不同。50例THA患者(64.9±9.9岁)和50例健康成人(64.5±8.9岁)的全身地上运动采用PCA分解为协调运动成分(“主要运动”,pm)。每个PM通过相对解释方差(rVAR;结构贡献)、PM加速度的过零次数(N;控制逆转/平滑度)和PM加速度的均方根(RMS;加速度幅度)来量化。前五个pm (p01 -5)映射到可识别的阶段:p01 -向前推进/推进;PM2-swing-phase运动;pm3 -单腿支撑+中外侧稳定;pm4 -躯干旋转单腿支撑;PM5-double-support过渡。与H1一致,从M0到M6患者的pmm2 rVAR增加(p = 0.005),所有pm的N降低(p≤0.003),PM3-5的RMS降低(p≤0.001)。与H2一致,在M6时,患者仍然表现出更高的rVAR趋势(未经调整p = 0.022,多重对照后不显著),PM3的RMS明显高于健康成人(p = 0.002)。这些研究结果表明,全髋关节置换术在6个月的时间里取得了实质性的进展,特别是在摆动阶段结构和整体平滑方面,但在单腿支撑期间(中外侧稳定),阶段特异性偏差仍然存在,这突出了延长康复以改善行走性能的目标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of biomechanics
Journal of biomechanics 生物-工程:生物医学
CiteScore
5.10
自引率
4.20%
发文量
345
审稿时长
1 months
期刊介绍: The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership. Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to: -Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells. -Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions. -Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response. -Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing. -Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine. -Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction. -Molecular Biomechanics - Mechanical analyses of biomolecules. -Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints. -Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics. -Sports Biomechanics - Mechanical analyses of sports performance.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书