Adherence to Physical Activity Interventions in Major Depressive Disorder: A Systematic Review and Meta-Analysis.

IF 9 1区医学 Q1 PSYCHIATRY

Psychotherapy and Psychosomatics Pub Date : 2026-01-30 DOI:10.1159/000550802

Vanessa K Tassone,Qiaowei Lin,Gloria Li,Aarna Rao,Victoria Duscio,Tia Mathur,Harani Uthayakumar,Syeda Zauraiz Sohail,Soha Kar,Danika A Quesnel,Wendy Lou,David Wiljer,Catherine M Sabiston,Benoit Mulsant,Venkat Bhat

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引用次数: 0

Abstract

INTRODUCTION Non-adherence is a barrier to the effectiveness of physical activity (PA) interventions for major depressive disorder (MDD). This systematic review and meta-analysis identified reported adherence-related outcomes, compared adherence rates of PA and non-PA interventions in MDD, and determined predictors of adherence. METHODS MEDLINE, APA PsycINFO, CINAHL Plus, and SPORTDiscus were searched until September 5th, 2024. Pooled estimated risk differences [RDs] and 95% confidence intervals [CIs] were calculated using fixed-effects or random-effects models. Meta-regression explored predictors of adherence. RESULTS Ninety-seven studies were included in this review, and 91 studies in the meta-analysis. Adherence-related outcomes for analyses included rates of intervention receipt, retention, protocol adherence, and session attendance. Retention was the most commonly reported outcome, with no significant difference between PA and non-PA interventions. Similarly, there were no significant differences in intervention receipt and session attendance. However, PA interventions had significantly lower protocol adherence than non-PA interventions (RD = -0.15; 95% CI: -0.23, -0.08). Severe baseline depressive symptoms, longer intervention durations, and in-person delivery predicted retention rates. Longer PA sessions predicted intervention receipt and supervision of activities predicted attendance rates. CONCLUSION Participants with MDD demonstrate lower protocol adherence to PA interventions than to interventions without a PA component. This result was based on a paucity of studies. Rates of intervention receipt, retention, and attendance were comparable in PA and non-PA interventions. Studies could benefit from including individuals with greater depressive symptom severity and supervised activity. With replication, findings could improve the design of, and increase adherence to, PA interventions in MDD.

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坚持体育活动干预重度抑郁症：系统回顾和荟萃分析。

不依从性是影响身体活动（PA）干预治疗重度抑郁症（MDD）有效性的一个障碍。本系统综述和荟萃分析确定了报告的依从性相关结果，比较了重度抑郁症中PA和非PA干预的依从率，并确定了依从性的预测因素。方法检索至2024年9月5日的文献：medline、APA PsycINFO、CINAHL Plus和SPORTDiscus。使用固定效应或随机效应模型计算汇总估计风险差异[rd]和95%置信区间[ci]。元回归探讨了依从性的预测因素。结果本综述纳入97项研究，meta分析纳入91项研究。依从性相关的分析结果包括干预接受率、保留率、协议依从性和会议出席率。保留是最常见的报道结果，在PA和非PA干预之间没有显著差异。同样，在接受干预和参加会议方面也没有显著差异。然而，PA干预的方案依从性明显低于非PA干预（RD = -0.15; 95% CI: -0.23, -0.08）。严重的基线抑郁症状，较长的干预持续时间和亲自递送预测保留率。更长的PA会话预测干预接收和监督活动预测出勤率。结论：重度抑郁症患者对PA干预的依从性低于不含PA成分的干预。这一结果是基于研究的缺乏。在PA和非PA干预中，干预的接受率、保留率和出勤率是相当的。研究可能会受益于包括抑郁症状严重程度更大的个体和监督活动。通过重复研究，研究结果可以改进MDD的PA干预措施的设计，并增加对其的依从性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychotherapy and Psychosomatics 医学-精神病学

CiteScore

29.40

自引率

6.10%

发文量

期刊介绍： Psychotherapy and Psychosomatics is a reputable journal that has been published since 1953. Over the years, it has gained recognition for its independence, originality, and methodological rigor. The journal has been at the forefront of research in psychosomatic medicine, psychotherapy research, and psychopharmacology, and has contributed to the development of new lines of research in these areas. It is now ranked among the world's most cited journals in the field. As the official journal of the International College of Psychosomatic Medicine and the World Federation for Psychotherapy, Psychotherapy and Psychosomatics serves as a platform for discussing current and controversial issues and showcasing innovations in assessment and treatment. It offers a unique forum for cutting-edge thinking at the intersection of medical and behavioral sciences, catering to both practicing clinicians and researchers. The journal is indexed in various databases and platforms such as PubMed, MEDLINE, Web of Science, Science Citation Index, Social Sciences Citation Index, Science Citation Index Expanded, BIOSIS Previews, Google Scholar, Academic Search, and Health Research Premium Collection, among others.