Adiponectin response to high-intensity interval training in overweight and obese individuals: a systematic review and meta-analysis.

IF 7.5 2区医学 Q1 Medicine

British medical bulletin Pub Date : 2026-01-02 DOI:10.1093/bmb/ldag002

Saber Saedmocheshi, Ghazi Racil, Aref Mehdipour, Mohamed Tounsi, Yassin Trabelsi, Ehsan Amiri, Gian Mario Migliaccio, Karim Chamari, Nicola Maffulli, Johnny Padulo

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引用次数: 0

Abstract

Background: Adipose tissue secretes bioactive substances, adipokines, which affect cardiovascular health. The secretion of adinopectines is associated with decreases in metabolic and cardiovascular diseases risk-factors such as obesity and type 2 diabetes. High-intensity interval training (HIIT) exerts beneficial effects on cardiometabolic health, but its effect on adipokines is unclear.

Sources of data: This systematic review and meta-analysis, aimed to report the effects of HIIT on adiponectin levels in overweight and obese individuals, was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The literature search was conducted in Web of Science, PubMed, ScienceDirect, and Google Scholar. The quality of the articles was evaluated using the Downs and Black checklist.

Areas of agreement: HIIT training generally did not affect adiponectin levels in overweight and obese individuals. Most likely, this effect can result from the lack of weight loss of the subjects in some studies.

Areas of controversy: One notable constraint within the scope of these investigations pertains to the relatively modest sample sizes employed. Consequently, future research endeavours should employ larger cohorts to enhance the generalizability of findings.

Growing points: HIIT focused on weight loss and fat percentage may effectively enhance the impact of HIIT on adiponectin levels.

Areas timely for developing research: Future research should implement rigorous dietary controls to isolate the independent effects of HIIT on adiponectin modulation.

Prospero registration: CRD42024580266.

查看原文本刊更多论文

超重和肥胖个体对高强度间歇训练的脂联素反应：系统回顾和荟萃分析。

背景：脂肪组织分泌生物活性物质，脂肪因子，影响心血管健康。腺嘌呤的分泌与代谢和心血管疾病风险因素（如肥胖和2型糖尿病）的减少有关。高强度间歇训练（HIIT）对心脏代谢健康有益，但其对脂肪因子的影响尚不清楚。数据来源：本系统回顾和荟萃分析，旨在报告HIIT对超重和肥胖个体脂联素水平的影响，采用系统回顾和荟萃分析（PRISMA）指南的首选报告项目进行。文献检索在Web of Science、PubMed、ScienceDirect和b谷歌Scholar中进行。文章的质量使用Downs和Black检查表进行评估。一致的领域：HIIT训练通常不会影响超重和肥胖个体的脂联素水平。最有可能的是，在一些研究中，这种影响可能是由于受试者没有减肥造成的。争议领域：在这些调查范围内，一个值得注意的限制是所采用的相对适度的样本量。因此，未来的研究工作应采用更大的队列，以提高研究结果的普遍性。生长点：专注于减肥和脂肪百分比的HIIT可以有效地增强HIIT对脂联素水平的影响。及时开展研究的领域：未来的研究应实施严格的饮食控制，以分离HIIT对脂联素调节的独立影响。普洛斯彼罗注册：CRD42024580266。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

British medical bulletin 医学-医学：内科

CiteScore

13.10

自引率

1.50%

发文量

审稿时长

>12 weeks

期刊介绍： British Medical Bulletin is a multidisciplinary publication, which comprises high quality reviews aimed at generalist physicians, junior doctors, and medical students in both developed and developing countries. Its key aims are to provide interpretations of growing points in medicine by trusted experts in the field, and to assist practitioners in incorporating not just evidence but new conceptual ways of thinking into their practice.