Dong Ding , Kai Kang , Shaofang Li , Tianfang Xing , Wenjie Yang , Liuqiao Sun , Xinxin Liu , Yao Chen , Mingyi Xue , Zengli Yu , Zhan Gao
{"title":"Joint impact of heat and ozone exposure on mortality in Henan, central China","authors":"Dong Ding , Kai Kang , Shaofang Li , Tianfang Xing , Wenjie Yang , Liuqiao Sun , Xinxin Liu , Yao Chen , Mingyi Xue , Zengli Yu , Zhan Gao","doi":"10.1016/j.atmosenv.2026.121800","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Globally, the increasing frequency of extreme heat events and ozone pollution incidents has significantly intensified public health risks. However, empirical evidence regarding their synergistic impacts remains limited in central China.</div></div><div><h3>Methods</h3><div>A two-stage analysis was conducted using data from 121 counties in Henan (2013–2019). Quasi-Poisson generalized additive models were used to assess county-specific associations, adjusting for PM<sub>2</sub>.<sub>5</sub>, RH, and temporal trends. The combined effect of air temperature (non-linear) and ozone (linear) was captured through multiplicative interaction terms. Random-effects meta-analyses were applied to pool the results. Subgroup analyses examined differences by age, sex, marital status, and cause of death.</div></div><div><h3>Results</h3><div>During the study period, 1,280,429 deaths were recorded. Both high temperatures and elevated ozone levels were associated with increased mortality. Their joint effects were stronger than individual exposures. At high ozone levels, mortality risk increased by 2 percentage points (from 9.3 % to 11.3 %) between temperature distribution percentiles 75th and 99th. Under high-temperature conditions (31.4 °C, 90th percentile), a 10 μg/m<sup>3</sup> elevation in ozone was associated with a 0.94 % (95 % CI: 0.49 %–1.38 %) increase in mortality. Older adults, females, other marital statuses (including unmarried, divorced, or widowed), and those with cardiovascular or respiratory diseases were more susceptible to its effects.</div></div><div><h3>Conclusion</h3><div>High temperature and ozone synergistically increase mortality risk. Targeted interventions are needed to protect vulnerable groups under climate change.</div></div>","PeriodicalId":250,"journal":{"name":"Atmospheric Environment","volume":"369 ","pages":"Article 121800"},"PeriodicalIF":3.8000,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Atmospheric Environment","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1352231026000294","RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Globally, the increasing frequency of extreme heat events and ozone pollution incidents has significantly intensified public health risks. However, empirical evidence regarding their synergistic impacts remains limited in central China.
Methods
A two-stage analysis was conducted using data from 121 counties in Henan (2013–2019). Quasi-Poisson generalized additive models were used to assess county-specific associations, adjusting for PM2.5, RH, and temporal trends. The combined effect of air temperature (non-linear) and ozone (linear) was captured through multiplicative interaction terms. Random-effects meta-analyses were applied to pool the results. Subgroup analyses examined differences by age, sex, marital status, and cause of death.
Results
During the study period, 1,280,429 deaths were recorded. Both high temperatures and elevated ozone levels were associated with increased mortality. Their joint effects were stronger than individual exposures. At high ozone levels, mortality risk increased by 2 percentage points (from 9.3 % to 11.3 %) between temperature distribution percentiles 75th and 99th. Under high-temperature conditions (31.4 °C, 90th percentile), a 10 μg/m3 elevation in ozone was associated with a 0.94 % (95 % CI: 0.49 %–1.38 %) increase in mortality. Older adults, females, other marital statuses (including unmarried, divorced, or widowed), and those with cardiovascular or respiratory diseases were more susceptible to its effects.
Conclusion
High temperature and ozone synergistically increase mortality risk. Targeted interventions are needed to protect vulnerable groups under climate change.
期刊介绍:
Atmospheric Environment has an open access mirror journal Atmospheric Environment: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Atmospheric Environment is the international journal for scientists in different disciplines related to atmospheric composition and its impacts. The journal publishes scientific articles with atmospheric relevance of emissions and depositions of gaseous and particulate compounds, chemical processes and physical effects in the atmosphere, as well as impacts of the changing atmospheric composition on human health, air quality, climate change, and ecosystems.