Orthodontic adhesives incorporated with strontium-containing fluorapatite for improved remineralizing effect

IF 5.8 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of dentistry Pub Date : 2026-03-01 Epub Date: 2026-01-21 DOI:10.1016/j.jdent.2026.106518

Ji-Yeon Hong , Ji-Eun Kim , Jae-Sung Kwon

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引用次数: 0

Abstract

Objectives

This study aimed to develop novel orthodontic adhesives with remineralization effect to prevent white spot lesions (WSLs) by adding strontium-containing fluorapatite (Sr-FAp), fluorapatite (FAp), and strontium-containing hydroxyapatite (Sr-HAp).

Methods

The particles were synthesized and characterized. The experimental groups consisted of a commercial control (CC), control (30 wt % resin matrix + 70 wt % glass filler), and experimental groups with 17.5 wt % of filler replaced by Sr-FAp, FAp, or Sr-HAp. The brackets were bonded to the enamel surface and the shear bond strength (SBS) and adhesive remnant index were tested. The release of calcium (Ca), phosphorus (P), strontium (Sr), and fluoride (F) ions from adhesive specimens in distilled water was evaluated after 15, 30, 60 days. The remineralization effect was observed the microhardness and surface morphology using scanning electron microscopy with energy dispersive spectroscopy.

Results

Except for the FAp, no significant differences in SBS were observed (p > 0.05). Ion release results showed Ca, P, Sr, and F ions were detected in the Sr-FAp group up to 60 days. The Sr-FAp group showed the highest microhardness (p < 0.05), and the largest amount of fluorapatite-like layer (Ca/P: 1.69) was formed after 60 days of immersion.

Conclusion

The Sr-FAp group showed acceptable SBS while exhibiting the highest microhardness and the most pronounced formation of a fluorapatite-like layer, indicating its effectiveness in preventing WSLs during orthodontic treatment.

Clinical significance

The orthodontic adhesive containing Sr-FAp offers potential clinical benefits by preventing demineralization and promoting remineralization of the enamel surface surrounding orthodontic brackets.

Abstract Image

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正畸粘接剂加入含锶氟磷灰石改善再矿化效果

目的通过添加含锶氟磷灰石（Sr-FAp）、氟磷灰石（FAp）和含锶羟基磷灰石（Sr-HAp），开发具有再矿化作用的新型正畸粘接剂，预防白斑病变（wsl）。方法合成并对其进行表征。实验组由商业对照组（CC）、对照组（30 wt %树脂基质+ 70 wt %玻璃填料）和实验组（17.5 wt %填料由Sr-FAp、FAp或Sr-HAp代替）组成。将托槽与牙釉质表面粘接，测定其剪切粘接强度（SBS）和粘接残余指数。分别于15、30、60天后对黏附标本在蒸馏水中的钙（Ca）、磷(P)、锶（Sr）和氟(F)离子的释放进行评价。利用扫描电镜和能谱仪观察了再矿化效果的显微硬度和表面形貌。结果除FAp外，两组间SBS差异无统计学意义（p > 0.05）。离子释放结果显示，在Sr- fap组中，Ca、P、Sr和F离子的释放时间长达60天。Sr-FAp组显微硬度最高（p < 0.05），浸泡60 d后形成的氟磷灰石样层数量最多（Ca/ p: 1.69）。结论Sr-FAp组的SBS可接受，显微硬度最高，氟磷灰石样层形成最明显，表明其在正畸治疗中预防WSLs的有效性。含有Sr-FAp的正畸粘接剂具有防止牙槽牙釉质脱矿和促进牙釉质再矿化的潜在临床价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of dentistry 医学-牙科与口腔外科

CiteScore

7.30

自引率

11.40%

发文量

349

审稿时长

35 days

期刊介绍： The Journal of Dentistry has an open access mirror journal The Journal of Dentistry: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The Journal of Dentistry is the leading international dental journal within the field of Restorative Dentistry. Placing an emphasis on publishing novel and high-quality research papers, the Journal aims to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. Topics covered include the management of dental disease, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research. The Journal of Dentistry will publish original scientific research papers including short communications. It is also interested in publishing review articles and leaders in themed areas which will be linked to new scientific research. Conference proceedings are also welcome and expressions of interest should be communicated to the Editor.