Tooth loss among adults with and without presence of systemic diseases – Age and Gender matched case control study

Q1 Medicine

Journal of oral biology and craniofacial research Pub Date : 2026-03-01 Epub Date: 2026-01-20 DOI:10.1016/j.jobcr.2026.01.007

Deshpande Vijaya Lakshmi, S. Jagadeeswara Rao, Dolar Doshi, Twinkle Tiwari, Lunavath Preethi

{"title":"Tooth loss among adults with and without presence of systemic diseases – Age and Gender matched case control study","authors":"Deshpande Vijaya Lakshmi, S. Jagadeeswara Rao, Dolar Doshi, Twinkle Tiwari, Lunavath Preethi","doi":"10.1016/j.jobcr.2026.01.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Systemic diseases contribute to tooth loss by affecting immunity, circulation, and bone health. While most studies focus on elderly, this study assesses tooth loss among adults with and without systemic diseases to support early care.</div></div><div><h3>Aim</h3><div>To assess tooth loss among adults with and without systemic diseases in age- and gender-matched cases and controls.</div></div><div><h3>Design</h3><div>A case-control study was conducted among 280 adults (140 cases and 140 controls). Data on demographics, lifestyle factors (alcohol, smoking, oral hygiene), and systemic diseases were collected. Tooth loss was assessed using Tooth Loss Index. Statistical analysis included Chi-square, Mann-Whitney <em>U</em> test, logistic regression, and correlation analysis.</div></div><div><h3>Results</h3><div>Cases had higher rates of alcohol use, smoking, and poor oral hygiene (p < 0.05). Tooth loss was significantly higher among cases (87.1 %) than controls (50 %), with greater mean missing teeth and higher Tooth Loss Index scores. Low education, alcohol, and smoking were significantly associated with increased tooth loss. Cases had nearly four times higher odds of significant tooth loss (OR = 3.82, p = 0.0001), with a strong positive correlation. (r = 0.82, p = 0.0001).</div></div><div><h3>Conclusion</h3><div>Systemic diseases are strongly associated with increased tooth loss in adults, highlighting need for early oral health interventions.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"16 2","pages":"Article 101403"},"PeriodicalIF":0.0000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of oral biology and craniofacial research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212426826000072","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/20 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Systemic diseases contribute to tooth loss by affecting immunity, circulation, and bone health. While most studies focus on elderly, this study assesses tooth loss among adults with and without systemic diseases to support early care.

Aim

To assess tooth loss among adults with and without systemic diseases in age- and gender-matched cases and controls.

Design

A case-control study was conducted among 280 adults (140 cases and 140 controls). Data on demographics, lifestyle factors (alcohol, smoking, oral hygiene), and systemic diseases were collected. Tooth loss was assessed using Tooth Loss Index. Statistical analysis included Chi-square, Mann-Whitney U test, logistic regression, and correlation analysis.

Results

Cases had higher rates of alcohol use, smoking, and poor oral hygiene (p < 0.05). Tooth loss was significantly higher among cases (87.1 %) than controls (50 %), with greater mean missing teeth and higher Tooth Loss Index scores. Low education, alcohol, and smoking were significantly associated with increased tooth loss. Cases had nearly four times higher odds of significant tooth loss (OR = 3.82, p = 0.0001), with a strong positive correlation. (r = 0.82, p = 0.0001).

Conclusion

Systemic diseases are strongly associated with increased tooth loss in adults, highlighting need for early oral health interventions.

查看原文本刊更多论文

有和不存在全身性疾病的成年人牙齿脱落——年龄和性别匹配的病例对照研究

背景：全身性疾病通过影响免疫力、血液循环和骨骼健康而导致牙齿脱落。虽然大多数研究都集中在老年人身上，但本研究评估了有和没有全身性疾病的成年人的牙齿脱落情况，以支持早期护理。目的在年龄和性别匹配的病例和对照组中评估有和没有全身性疾病的成年人的牙齿脱落情况。设计对280名成人进行病例对照研究（140例和140例对照）。收集了人口统计学、生活方式因素（酒精、吸烟、口腔卫生）和全身性疾病的数据。采用牙损指数评估牙损情况。统计分析包括卡方检验、Mann-Whitney U检验、logistic回归和相关分析。结果患者饮酒、吸烟、口腔卫生不良发生率较高（p < 0.05）。病例中牙齿脱落率（87.1%）明显高于对照组（50%），平均缺失牙数和牙齿脱落指数得分均较高。受教育程度低、饮酒和吸烟与牙齿脱落的增加显著相关。病例发生明显牙齿脱落的几率高出近4倍（OR = 3.82, p = 0.0001），且呈正相关。（r = 0.82, p = 0.0001）。结论全身性疾病与成人牙齿脱落增加密切相关，强调早期口腔健康干预的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of oral biology and craniofacial research Medicine-Otorhinolaryngology

CiteScore

4.90

自引率

0.00%

发文量

133

审稿时长

167 days

期刊介绍： Journal of Oral Biology and Craniofacial Research (JOBCR)is the official journal of the Craniofacial Research Foundation (CRF). The journal aims to provide a common platform for both clinical and translational research and to promote interdisciplinary sciences in craniofacial region. JOBCR publishes content that includes diseases, injuries and defects in the head, neck, face, jaws and the hard and soft tissues of the mouth and jaws and face region; diagnosis and medical management of diseases specific to the orofacial tissues and of oral manifestations of systemic diseases; studies on identifying populations at risk of oral disease or in need of specific care, and comparing regional, environmental, social, and access similarities and differences in dental care between populations; diseases of the mouth and related structures like salivary glands, temporomandibular joints, facial muscles and perioral skin; biomedical engineering, tissue engineering and stem cells. The journal publishes reviews, commentaries, peer-reviewed original research articles, short communication, and case reports.