Novel significant associations between temperature-humidity index and HSP70 g.1117G>A with milk yield traits of Holstein-Friesian cows reared in semi-arid regions

IF 2.9 2区生物学 Q2 BIOLOGY

Journal of thermal biology Pub Date : 2026-02-01 Epub Date: 2026-01-21 DOI:10.1016/j.jtherbio.2026.104384

Mustafa Kibar , Ramazan Erkmen , Ertuğrul Kul , İbrahim Aytekin

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Abstract

This study aimed to determine the relationships between the HSP70 g.1117G > A gene and some milk production traits such as daily milk yield (DMY), conductivity (Cond), milking time (MT) and activity (Act) in Holstein-Friesian dairy cattle. Blood samples from the coccygeal vein of 203 Holstein-Friesian cows in different lactations were collected. The population, with A and G allele frequencies of 0.2365 and 0.7635 and AA, AG, GG genotype frequencies of 0.089, 0.295, and 0.616, was not in Hardy-Weinberg equilibrium (P < 0.01). The lowest DMY was in the THI<65 group, while the highest was in the 65≤THI<68 and THI≥68 groups. Regarding temperature-humidity index (THI), the lowest MT and Act values were recorded in the THI<65 group, while the highest were in the THI≥68 group. For DMY and Cond, the highest values were in AG and the lowest were in AA genotype cattle (P < 0.01). Regarding MT, the highest values were observed in the AA and AG, with the lowest in GG genotypes (P < 0.01). For Act, AG and GG genotypes showed the highest values, while AA had the lowest (P < 0.01). As a result, the G allele (sensitive to heat stress) could be beneficial for both increasing DMY and reducing MT. However, the threshold values for the THI should be re-evaluated based on the effectiveness of the cooling systems used and the specific conditions of the farm.

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温湿指数和HSP70 g.1117G>A与半干旱区荷斯泰因-弗里奶牛产奶量性状的新显著相关性

本研究旨在研究HSP70 g.1117G >； A基因与荷斯泰因-弗里奶牛日产奶量（DMY）、电导率（Cond）、挤奶时间（MT）和活性（Act）等产乳性状的关系。采集203头不同哺乳期荷斯泰因奶牛尾骨静脉血样。种群A、G基因型频率分别为0.2365、0.7635，AA、AG、GG基因型频率分别为0.089、0.295、0.616，不处于Hardy-Weinberg平衡（P < 0.01）。DMY以THI<；65组最低，65≤THI<；68和THI≥68组最高。温湿指数（THI） MT和Act值在THI≥65组最低，在THI≥68组最高。DMY和Cond以AG型最高，AA型最低（P < 0.01）。MT以AA和AG基因型最高，GG基因型最低（P < 0.01）。Act基因型以AG和GG基因型最高，AA基因型最低（P < 0.01）。因此，G等位基因（对热应激敏感）可能有利于增加DMY和降低MT。然而，THI的阈值应根据所使用的冷却系统的有效性和农场的具体条件重新评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of thermal biology 生物-动物学

CiteScore

5.30

自引率

7.40%

发文量

196

审稿时长

14.5 weeks

期刊介绍： The Journal of Thermal Biology publishes articles that advance our knowledge on the ways and mechanisms through which temperature affects man and animals. This includes studies of their responses to these effects and on the ecological consequences. Directly relevant to this theme are: • The mechanisms of thermal limitation, heat and cold injury, and the resistance of organisms to extremes of temperature • The mechanisms involved in acclimation, acclimatization and evolutionary adaptation to temperature • Mechanisms underlying the patterns of hibernation, torpor, dormancy, aestivation and diapause • Effects of temperature on reproduction and development, growth, ageing and life-span • Studies on modelling heat transfer between organisms and their environment • The contributions of temperature to effects of climate change on animal species and man • Studies of conservation biology and physiology related to temperature • Behavioural and physiological regulation of body temperature including its pathophysiology and fever • Medical applications of hypo- and hyperthermia Article types: • Original articles • Review articles