Components of cognitive-behavioral interventions to prevent the onset of depression among the high-risk population: a systematic review and component network meta-analysis

IF 4.3 2区心理学 Q1 PSYCHOLOGY, CLINICAL

Behaviour Research and Therapy Pub Date : 2026-02-01 Epub Date: 2026-01-12 DOI:10.1016/j.brat.2026.104960

Masatsugu Sakata , Ethan Sahker , Yan Luo , Tomohiro Takayama , Rie Toyomoto , Yuki Furukawa , So Sugita , Masami Ito , Masafumi Tada , Yukiko Honda , Sanae Kishimoto , Mathias Harrer , Claudia Buntrock , Antonia A. Sprenger , Clara Miguel , Pim Cuijpers , Toshi A. Furukawa

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引用次数: 0

Abstract

Objectives

Cognitive Behavioral Therapy (CBT) is a promising strategy for preventing onset of depression. This systematic review and component network meta-analysis (cNMA) investigated efficacious and harmful components including various skills and delivery formats of CBT for preventing depression onset among at-risk populations.

Eligibility criteria

We selected randomized trials of preventive CBT interventions from a previous systematic review (Cuijpers et al., 2021), and conducted an additional search on PubMed and PsycINFO up to January 2022.

Methods of synthesis

The primary outcome was incidence of diagnosed depression. Both intervention-level NMA and cNMA estimated the preventive effect of intervention arms and components.

Results

We identified 44 prevention trials (N = 9519). The intervention-level NMA demonstrated the preventive effects of CBT over no intervention (OR=0.52, 95 %CI: 0.39 to 0.69). There was some evidence from cNMA showing that problem-solving and behavioral activation may be beneficial in preventing depression. These two components combined in the unguided self-help or the group format showed an odds ratio of 0.25 (95 %CI: 0.08 to 0.81 ) and 0.31 (95 %CI: 0.15 to 0.64), respectively. We developed a web application estimating the relative and absolute effects of various combinations of components (https://yan-luo.shinyapps.io/cNMA_depression/).

Conclusion

Our results support the preventive effect of CBT on depression onset. In particular, efficacious depression prevention interventions can include problem-solving and behavioral activation.

查看原文本刊更多论文

预防高危人群抑郁发作的认知行为干预成分：系统回顾和成分网络荟萃分析。

目的：认知行为疗法（CBT）是一种很有前途的预防抑郁症发作的策略。本系统综述和成分网络荟萃分析（cNMA）调查了CBT预防高危人群抑郁发作的有效和有害成分，包括各种技能和交付形式。入选标准：我们从之前的系统综述中选择了预防性CBT干预的随机试验（Cuijpers等，2021），并在PubMed和PsycINFO上进行了额外的检索，截止到2022年1月。综合方法：主要观察指标为诊断抑郁症的发生率。干预水平的NMA和cNMA均评估了干预武器和成分的预防效果。结果：我们确定了44项预防试验（N = 9519）。干预水平的NMA显示CBT的预防效果优于不干预（OR=0.52, 95% CI: 0.39至0.69）。cNMA的一些证据表明，问题解决和行为激活可能有助于预防抑郁症。这两个组成部分在无指导自助或小组形式中分别显示0.25 （95% CI: 0.08至0.81）和0.31 （95% CI: 0.15至0.64）的优势比。我们开发了一个web应用程序来评估各种组件组合的相对和绝对效果（https://yan-luo.shinyapps.io/cNMA_depression/）。结论：本研究结果支持CBT对抑郁症发作的预防作用。特别是，有效的抑郁症预防干预可以包括解决问题和行为激活。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Behaviour Research and Therapy PSYCHOLOGY, CLINICAL-

CiteScore

7.50

自引率

7.30%

发文量

148

期刊介绍： The major focus of Behaviour Research and Therapy is an experimental psychopathology approach to understanding emotional and behavioral disorders and their prevention and treatment, using cognitive, behavioral, and psychophysiological (including neural) methods and models. This includes laboratory-based experimental studies with healthy, at risk and subclinical individuals that inform clinical application as well as studies with clinically severe samples. The following types of submissions are encouraged: theoretical reviews of mechanisms that contribute to psychopathology and that offer new treatment targets; tests of novel, mechanistically focused psychological interventions, especially ones that include theory-driven or experimentally-derived predictors, moderators and mediators; and innovations in dissemination and implementation of evidence-based practices into clinical practice in psychology and associated fields, especially those that target underlying mechanisms or focus on novel approaches to treatment delivery. In addition to traditional psychological disorders, the scope of the journal includes behavioural medicine (e.g., chronic pain). The journal will not consider manuscripts dealing primarily with measurement, psychometric analyses, and personality assessment.