Predicting intraoperative transfusion volumes of blood products in cardiovascular surgery: a retrospective study

IF 1.2 4区医学 Q4 HEMATOLOGY

Transfusion and Apheresis Science Pub Date : 2026-04-01 Epub Date: 2026-01-15 DOI:10.1016/j.transci.2026.104374

Hiroki Shibata , Yuma Hirano , Mikihiro Shimizu , Kaede Ino , Akiho Ikeda , Yui Nagae , Naoki Nemoto , Mizuki Oishi , Takahito Shinba , Chiaki Yamada , Keiko Ishizuka , Takaaki Ono

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引用次数: 0

Abstract

Background and Objectives

Red blood cells are often overprepared for surgery, leading to waste and increased costs, despite the need for cross-matching tests. This study aimed to develop a model for predicting the number of red blood cell units required during cardiovascular surgery using patient characteristics.

Materials and Methods

This retrospective study included patients who underwent cardiovascular surgery at our hospital from April 2022 to October 2022. Multiple regression analysis was performed using preoperative patient attributes and blood data, with red blood cell units used during surgery as the objective variable. Models were developed using patient demographics and blood data, with additional models incorporating specific surgical procedures to assess predictive accuracy.

Results

Model 1 included age, sex, weight, hematocrit, prothrombin time-international normalized ratio, serum creatinine, volume of preoperatively donated diluted autologous blood, and history of cardiovascular surgery. Model 2 included the same variables as Model 1, plus aortic aneurysm resection as a surgical procedure. The predictive equations of the study showed superior accuracy for both Model 1 and Model 2 compared to the conventional red blood cell units requested by physicians or those predicted using the surgical blood order equation based on correlation coefficients. Model 2 outperformed both Model 1 and conventional methods in predictive utility.

Conclusion

This study developed a clinically useful formula for predicting the number of red blood cell units required during surgery based on preoperative patient-specific data, without restricting the analysis to specific procedures. This formula may improve blood product inventory management and reduce medical costs.

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预测心血管手术术中血液制品输血量：一项回顾性研究

背景与目的尽管需要进行交叉配型试验，但手术时红细胞往往准备过度，导致浪费和成本增加。本研究旨在建立一种模型，利用患者特征预测心血管手术期间所需的红细胞数量。材料与方法回顾性研究纳入2022年4月至2022年10月在我院行心血管手术的患者。采用术前患者属性和血液数据进行多元回归分析，以术中使用的红血球单位为客观变量。使用患者人口统计数据和血液数据建立模型，并结合特定的外科手术过程来评估预测的准确性。结果模型1包括年龄、性别、体重、红细胞压积、凝血酶原时间-国际标准化比值、血清肌酐、术前捐献稀释自体血容量、心血管手术史。模型2包括与模型1相同的变量，加上主动脉瘤切除术作为外科手术。该研究的预测方程显示，与医生要求的传统红细胞单位或基于相关系数的外科血序方程预测的红细胞单位相比，模型1和模型2的准确性更高。模型2在预测效用上优于模型1和传统方法。本研究开发了一个临床有用的公式，可以根据术前患者特异性数据预测手术期间所需的红细胞数量，而不局限于特定的手术过程。该配方可改善血液制品库存管理，降低医疗成本。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transfusion and Apheresis Science 医学-血液学

CiteScore

3.60

自引率

5.30%

发文量

181

审稿时长

42 days

期刊介绍： Transfusion and Apheresis Science brings comprehensive and up-to-date information to physicians and health care professionals involved in the rapidly changing fields of transfusion medicine, hemostasis and apheresis. The journal presents original articles relating to scientific and clinical studies in the areas of immunohematology, transfusion practice, bleeding and thrombotic disorders and both therapeutic and donor apheresis including hematopoietic stem cells. Topics covered include the collection and processing of blood, compatibility testing and guidelines for the use of blood products, as well as screening for and transmission of blood-borne diseases. All areas of apheresis - therapeutic and collection - are also addressed. We would like to specifically encourage allied health professionals in this area to submit manuscripts that relate to improved patient and donor care, technical aspects and educational issues. Transfusion and Apheresis Science features a "Theme" section which includes, in each issue, a group of papers designed to review a specific topic of current importance in transfusion and hemostasis for the discussion of topical issues specific to apheresis and focuses on the operators'' viewpoint. Another section is "What''s Happening" which provides informal reporting of activities in the field. In addition, brief case reports and Letters to the Editor, as well as reviews of meetings and events of general interest, and a listing of recent patents make the journal a complete source of information for practitioners of transfusion, hemostasis and apheresis science. Immediate dissemination of important information is ensured by the commitment of Transfusion and Apheresis Science to rapid publication of both symposia and submitted papers.