Seroprevalence and risk factors for Anaplasma marginale seropositivity in cattle in California between 2010 and April 2023

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases Pub Date : 2026-01-01 Epub Date: 2026-01-14 DOI:10.1016/j.ttbdis.2026.102604

SY Chen , A Hill , W Jackson , M Saunders , B Munk , J Foley , S Gassama , G Maier

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Abstract

The objectives of this study were to estimate prevalence of A. marginale infection in cattle in California and to identify potential risk factors for infection including weather effects. We considered individual-level prevalence the percentage of positive individual test results and submission-level prevalence the percentage of submissions from the same owner at the same time with at least one animal testing positive for Anaplasma. A total of 3684 Anaplasma test results from 773 submissions to the California Animal Health and Food Safety Laboratory between January 2010 and April 2023 were used in this study. Time series analysis and generalized estimating equations (GEEs) were used to analyze the data. Abundance of Dermacentor ticks in California was mapped. The overall true prevalence of Anaplasma infection at the individual level was 23.7% (95% CI: 22.3 – 25.2%) with a submission-level prevalence of 38.3% (95% CI: 34.9 – 41.8%) in cattle in California. A seasonal change in seroprevalence was observed in time series analysis, with lower seroprevalence in wet seasons than in dry seasons. Higher odds of Anaplasma positivity were found in cattle two years of age or older, beef cattle, with lower average ambient temperatures in the dry season, and higher average ambient temperatures in the wet season in GEEs.

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2010年至2023年4月加州牛无原体边缘血清阳性的血清流行率和危险因素

本研究的目的是估计加州牛中边缘螺旋体感染的流行程度，并确定包括天气影响在内的潜在感染风险因素。我们考虑了个体水平的流行率，即个体检测结果阳性的百分比，以及提交水平的流行率，即同一主人在同一时间内至少有一只动物无原体检测呈阳性的百分比。本研究使用了2010年1月至2023年4月期间向加州动物健康和食品安全实验室提交的773份无原体检测结果中的3684份。采用时间序列分析和广义估计方程（GEEs）对数据进行分析。绘制了加州革螨蜱的丰度。在加利福尼亚的牛中，个体水平上无原体感染的总体真实患病率为23.7% (95% CI: 22.3 - 25.2%)，提交水平的患病率为38.3% （95% CI: 34.9 - 41.8%）。在时间序列分析中观察到血清阳性率的季节变化，雨季的血清阳性率低于旱季。在两岁或两岁以上的肉牛中发现无原体阳性的几率较高，在干旱季节平均环境温度较低，而在GEEs的雨季平均环境温度较高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ticks and Tick-borne Diseases INFECTIOUS DISEASES-MICROBIOLOGY

CiteScore

6.90

自引率

12.50%

发文量

185

审稿时长

6-12 weeks

期刊介绍： Ticks and Tick-borne Diseases is an international, peer-reviewed scientific journal. It publishes original research papers, short communications, state-of-the-art mini-reviews, letters to the editor, clinical-case studies, announcements of pertinent international meetings, and editorials. The journal covers a broad spectrum and brings together various disciplines, for example, zoology, microbiology, molecular biology, genetics, mathematical modelling, veterinary and human medicine. Multidisciplinary approaches and the use of conventional and novel methods/methodologies (in the field and in the laboratory) are crucial for deeper understanding of the natural processes and human behaviour/activities that result in human or animal diseases and in economic effects of ticks and tick-borne pathogens. Such understanding is essential for management of tick populations and tick-borne diseases in an effective and environmentally acceptable manner.