Cherenkov emission-based quality assurance for linear accelerators.

IF 2.1 4区 医学 Q2 BIOLOGY
Hiroyuki Okamoto, Fuma Tojo, Kazuyoshi Kurita, Miyuki Murata, Masataka Ueda, Aya Shimoike, Yuka Kondou, Yukio Fujita, Yuna Nakajima, Satoshi Nakamura, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Tetsu Nakaichi, Hiroshi Igaki
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Abstract

When electrons exceed the speed of light in a medium, they emit low-intensity visible light, known as Cherenkov emission (CE). This study proposes a novel CE-based quality assurance (QA) test for linear accelerators. A CE-based QA (C-QA) phantom incorporating a mock tumor and four CE observation plates (top, bottom, left, and right) was developed. After tumor-based alignment using cone-beam computed tomography (CBCT), lateral and posterior fields were used for irradiation. A C-Dose camera was employed to measure the treatment position, gantry angle, photon energy (TPR20,10), and CE counts for both fields. The treatment position and TPR20,10 were determined by analyzing the changes in the CE profile, while the gantry angle was calculated based on the tilt between the entry and exit field positions. Confidence limits were evaluated over a three-month period, during which long-term testing demonstrated favorable results. The standard deviations (σ) for CBCT-based positional accuracy and gantry angle were within ±1 mm in all three directions and within 1°, respectively. The mean ± σ for TPR20,10 was 0.631 ± 0.004, closely matching the 0.629 measured using an ionization chamber. Detected CE counts exhibited a higher variation (σ = 2.7%). CE-based QA appears to be an effective and reliable method for radiotherapy. Treatment position could be directly measured without conventional dosimetric devices, while CE imaging simultaneously evaluated positional accuracy, gantry angle, and photon energy (TPR20,10). However, accurate assessment of linear accelerator dose output remains a challenge, and the quantification of CE counts requires further investigation.

Abstract Image

Abstract Image

Abstract Image

基于切伦科夫排放的直线加速器质量保证。
当电子在介质中超过光速时,它们会发出低强度的可见光,称为切伦科夫辐射(CE)。本研究提出一种新的基于ce的直线加速器质量保证(QA)测试方法。制作基于CE的QA (C-QA)假体,包括模拟肿瘤和四个CE观察板(上、下、左、右)。在使用锥形束计算机断层扫描(CBCT)对肿瘤进行定位后,使用侧野和后野进行照射。采用C-Dose相机测量两个场的治疗位置、龙门架角度、光子能量(TPR20、10)和CE计数。通过分析CE剖面的变化确定处理位置和TPR20、10,根据进出场位置之间的倾斜度计算龙门角度。在三个月的时间内评估置信限,在此期间,长期测试显示出良好的结果。基于cbct的定位精度和龙门角度的标准差(σ)在三个方向上均在±1 mm以内,在1°以内。tpr20,10的平均±σ为0.631±0.004,与电离室测量的0.629非常接近。检测到的CE计数变化较大(σ = 2.7%)。基于ce的QA似乎是一种有效和可靠的放疗方法。无需常规剂量仪即可直接测量治疗位置,而CE成像可同时评估位置精度、龙门角度和光子能量(tpr20,10)。然而,准确评估直线加速器的剂量输出仍然是一个挑战,CE计数的量化需要进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.60
自引率
5.00%
发文量
86
审稿时长
4-8 weeks
期刊介绍: The Journal of Radiation Research (JRR) is an official journal of The Japanese Radiation Research Society (JRRS), and the Japanese Society for Radiation Oncology (JASTRO). Since its launch in 1960 as the official journal of the JRRS, the journal has published scientific articles in radiation science in biology, chemistry, physics, epidemiology, and environmental sciences. JRR broadened its scope to include oncology in 2009, when JASTRO partnered with the JRRS to publish the journal. Articles considered fall into two broad categories: Oncology & Medicine - including all aspects of research with patients that impacts on the treatment of cancer using radiation. Papers which cover related radiation therapies, radiation dosimetry, and those describing the basis for treatment methods including techniques, are also welcomed. Clinical case reports are not acceptable. Radiation Research - basic science studies of radiation effects on livings in the area of physics, chemistry, biology, epidemiology and environmental sciences. Please be advised that JRR does not accept any papers of pure physics or chemistry. The journal is bimonthly, and is edited and published by the JRR Editorial Committee.
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