Simultaneous Therapy Approach: Systemic and Intratympanic Corticosteroid for Idiopathic Sudden Sensorineural Hearing Loss: A Clinical Study.

Q3 Medicine

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI:10.22038/ijorl.2025.89180.3984

Mohsen Rajati, Imaneh Roshanzamir, Ermia Mousavi Mohammadi, Romina Tavasoli, Sadegh Jafarzadeh

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Abstract

Introduction: Idiopathic Sudden sensorineural hearing loss (ISSNHL) can be treated with various methods. This study investigated the impact of combined systemic and intratympanic corticosteroid injections on hearing improvement and associated symptoms in patients with ISSNHL.Top of Form.

Materials and methods: The study investigated the recovery process of 73 patients with ISSNHL from Khorasan Razavi registry between the years 2022 to 2024. These patients received treatment involving both systemic and intratympanic corticosteroid.

Results: One month after treatment, the study using Modified Siegel's criteria found complete, partial, and slight improvement in 30%, 14%, and 16% of patients, respectively. During this period, 24% of cases with tinnitus were completely treated, while 51% experienced partial relief. For cases with vertigo, 67% were completely treated, and 33% had partial improvement.

Conclusion: Combined corticosteroid treatment is effective in approximately sixty percent of ISSNHL cases. This therapy also demonstrates success in alleviating related symptoms such as tinnitus and vertigo.

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同时治疗方法：全身和鼓腔内皮质类固醇治疗特发性突发性感音神经性听力损失：一项临床研究。

特发性突发性感音神经性听力损失（ISSNHL）的治疗方法多种多样。本研究探讨了全身和鼓室内联合注射皮质类固醇对ISSNHL患者听力改善和相关症状的影响。顶端的形式。材料与方法：本研究调查了呼罗珊-拉扎维（Khorasan Razavi）登记的73例ISSNHL患者在2022 - 2024年间的康复过程。这些患者接受了包括全身和鼓室内皮质类固醇的治疗。结果：治疗一个月后，采用改良Siegel标准的研究分别发现30%、14%和16%的患者完全、部分和轻微改善。在此期间，24%的耳鸣患者得到了完全治疗，51%的耳鸣患者得到了部分缓解。对于眩晕的病例，67%得到完全治疗，33%得到部分改善。结论：皮质类固醇联合治疗对大约60%的ISSNHL病例有效。这种疗法在缓解耳鸣和眩晕等相关症状方面也取得了成功。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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