Epileptogenicidad después de estereoelectroencefalografía y monitorización invasiva de rejillas subdurales: un análisis retrospectivo de pacientes adultos y pediátricos con epilepsia refractaria

IF 0.8 4区医学 Q4 NEUROSCIENCES

Neurocirugia Pub Date : 2026-01-01 Epub Date: 2025-09-30 DOI:10.1016/j.neucir.2025.500703

Sonia Pulido , Sven Ivankovic , Nolan Winslow , Andrés Maldonado

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引用次数: 0

Abstract

Objective

To assess if removal of stereoelectroencephalography (SEEG) or subdural grids (SDG) is associated with an increased seizure frequency in patients with refractory epilepsy during the immediate postoperative period.

Methods

37 patients with refractory epilepsy that underwent monitoring with SEEG or SDG during November 2012-March 2022 were identified using electronic medical records from asingle institution. Seizure history, duration of intracranial monitoring, and monitored brain regions were recorded.

Results

5.0% and 5.9% of SEEG and SDG patients had a seizure within 48 h post-termination of monitoring. 25% and 11.8% of SEEG and SDG patients had a seizure between 48 h and 1-week after surgery. Between 1 week and 1 month after SEEG or SDG removal, 35% and 41.2% of patients had a seizure. 30% and 50% SEEG or SDG patients had a seizure between 1- and 2-months following removal. Overall change in postoperative seizure frequency was not significant. Seizure frequency increased for 11.8% of SDG patients while frequency remained unchanged for 5.9% and decreased for 82.4%. No patients post-SEEG removal in our cohort experienced an increased seizure frequency. 95% experienced a decrease in seizure frequency and no change was observed in 5%.

Conclusion

SEEG is not associated with increased epileptogenicity after termination of monitoring. Two patients post-SDG removal experienced an increase in seizure frequency. While patients with refractory epilepsy may continue to have seizures during the immediate postoperative period, it is likely that patients will experience a decrease in seizure frequency after removal of SEEG or SDG.

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立体脑电图和侵入性硬膜下网状监测后的癫痫原性：成人和儿童顽固性癫痫患者的回顾性分析

目的评估术后立即切除立体脑电图（SEEG）或硬脑膜下网格（SDG）是否与难治性癫痫患者发作频率增加有关。方法选取2012年11月至2022年3月期间接受SEEG或SDG监测的37例难治性癫痫患者，使用来自同一机构的电子病历。记录癫痫发作史、颅内监测持续时间及监测的脑区。结果SEEG和SDG患者在监测终止后48 h内癫痫发作的比例分别为5.0%和5.9%。25%和11.8%的SEEG和SDG患者在术后48小时至1周内发生癫痫发作。在SEEG或SDG切除后1周至1个月，35%和41.2%的患者发生癫痫发作。30%和50%的SEEG或SDG患者在切除后1至2个月发生癫痫发作。术后癫痫发作频率的总体变化不显著。11.8%的SDG患者癫痫发作频率增加，5.9%的患者癫痫发作频率不变，82.4%的患者癫痫发作频率下降。在我们的队列中，没有患者在切除seeg后癫痫发作频率增加。95%的患者癫痫发作频率下降，5%的患者无变化。结论终止监测后seeg与致痫性增高无相关性。2例患者在sdg移除后癫痫发作频率增加。虽然难治性癫痫患者可能在术后立即继续发作，但在切除SEEG或SDG后，患者的发作频率可能会降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurocirugia 医学-神经科学

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

60 days

期刊介绍： Neurocirugía is the official Journal of the Spanish Society of Neurosurgery (SENEC). It is published every 2 months (6 issues per year). Neurocirugía will consider for publication, original clinical and experimental scientific works associated with neurosurgery and other related neurological sciences. All manuscripts are submitted for review by experts in the field (peer review) and are carried out anonymously (double blind). The Journal accepts works written in Spanish or English.