Sleep and chronic rhinosinusitis: a systematic review of postoperative data.

Abstract

Introduction: Patients with nasal obstruction due to chronic rhinosinusitis with nasal polyposis may present with altered sleep quality. Data on this subject in the literature remains scarce.

Objectives: To evaluate changes in sleep quality and polysomnographic parameters among patients who underwent functional endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis.

Materials and methods: A systematic review was performed in three databases: PubMed, Cochrane, and Embase. The following keywords were used: chronic rhinosinusitis, nasal polyposis, sleep quality, and nasosinusal endoscopic surgery. Studies evaluating adults with nasal polyposis who underwent endoscopic nasosinusal surgery were selected. A meta-analysis was conducted to compare mean scores for polysomnographic and subjective variables from before to after the operation.

Results: A systematic review and meta-analysis of three studies were performed, only one of which was randomized. The total sample consisted of 64 patients. There was a decrease in the mean AHI score and improvements in mean and minimum saturation. The mean difference in percentage of stage N3 from before to after the operation was 1.12 with a 95% CI from -3.51 to 5.75, which was non-significant. There was a mean percentage increase in REM sleep duration and a decrease in PSQI scores, which were both statistically significant ( p  < 0.05).

Conclusion: There were improvements in the quality of sleep and duration of REM sleep after surgery, with no improvement in polysomnographic respiratory parameters.