Osborn waves secondary to hypercalcemia in a dog

Abstract

A seven-year-old female spayed Vizsla was presented on referral for evaluation after ingesting a toxic dose of a vitamin D analogue (calciportriol). The owners had noted vomiting, ptyalism, and polydipsia prior to evaluation. Blood work was performed, which confirmed a severe ionized hypercalcemia, and the dog was admitted for medical management of the hypercalcemia. An electrocardiogram was performed due to the severity of the hypercalcemia, which revealed Osborn waves. While Osborn waves have been reported in cases of hypercalcemia in humans, this is the first case of Osborn waves in a dog associated with severe hypercalcemia.