Gamma irradiation as a green technology to enhance antifungal efficacy of Ageratum conyzoides extract for sustainable crop protection

Sustainable Chemistry One World Pub Date : 2026-03-01 Epub Date: 2025-12-22 DOI:10.1016/j.scowo.2025.100170

Nguyen Thi Nhu Quynh , Tran Thi Thu Phuong , Nguyen Thi Hong Thuong , Han Ngoc Bui , Dang-Khoa Phan , Nguyen Ngoc Duy

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Abstract

Gamma irradiation is a promising green technology for improving the functional quality of plant-based bioresources. This study evaluates the effect of gamma irradiation (0–10 kGy) on the phytochemical composition and antifungal activity of Ageratum conyzoides ethanolic extracts against Fusarium oxysporum. Moderate irradiation doses (4–6 kGy) significantly enhanced secondary metabolites, including flavonoids, saponins and alkaloids, leading to significantly enhanced the extract's antifungal efficacy. At 4 kGy, the extract achieved a maximum inhibition of 95.06 % at 8 % concentration, coinciding with peak flavonoid content (34.00 ± 1.03 mg/mL). However, higher doses (≥8 kGy) degraded bioactive compounds, reducing efficacy. These findings highlight gamma irradiation as an eco-friendly post-extraction treatment to boost natural antifungal agents, contributing to sustainable agriculture and reduced reliance on synthetic fungicides.

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伽马辐照作为一种绿色技术提高刺蒺藜提取物的抗真菌效果，用于可持续作物保护

伽马辐射是一种很有前途的绿色技术，可以提高植物性生物资源的功能质量。本文研究了γ辐照（0-10 kGy）对鹰掌藤乙醇提取物对尖孢镰刀菌的化学成分和抑菌活性的影响。中等照射剂量（4-6 kGy）显著提高了黄酮、皂苷和生物碱等次生代谢物的抗真菌活性。在4 kGy浓度下，8 %浓度下，提取液的最大抑制率为95.06 %，与黄酮含量峰值（34.00 ± 1.03 mg/mL）一致。然而，较高剂量（≥8 kGy）会降解生物活性化合物，降低疗效。这些发现强调了伽马辐射作为一种环保的提取后处理方法，可以促进天然抗真菌剂，有助于可持续农业和减少对合成杀菌剂的依赖。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Sustainable Chemistry One World

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