Effects of millet consumption on metabolic homeostasis (glycemic control and lipid profiles) in adults: A systematic review

IF 4.4 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes & Metabolic Syndrome-Clinical Research & Reviews Pub Date : 2026-01-01 Epub Date: 2025-12-19 DOI:10.1016/j.dsx.2025.103359

Nisarga S. Naik , Nikhil Nadiger , Arpita Mukhopadhyay

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引用次数: 0

Abstract

Objective

The aim of the study was to systematically review the literature to analyze the effect of millet consumption on metabolic homeostasis in adults.

Method

We conducted a systematic review of literature to evaluate effect of millet-consumption on metabolic homeostasis. Science Direct and PubMed databases were used to search articles till January 14th, 2025. Quality of randomized-controlled and crossover-studies were reported using the Cochrane-Risk-of-Bias-Assessment-scale, while that of non-randomized studies were reported using the Risk-of-Bias-in-Non-Randomized-Studies-of-Interventions-scale.

Results

One randomized-controlled study, three randomized-crossover studies, and two non-randomized studies were included. In participants with type 2 diabetes (T2DM), multigrain rotis prepared from finger millet, foxtail millet, sorghum, jowar, oats and maize reduced glycated hemoglobin (HbA1c) and low density lipoprotein cholesterol (LDL-c) levels, foxtail millet dosas reduced postprandial blood glucose levels and food prepared from heat-treated barnyard grains reduced fasting blood glucose (FBG) and LDL-c levels. Food prepared from powdered finger millet and little millet reduced FBG levels in prediabetics.

Conclusion

Consumption of millet-based foods could improve glycemic response and LDL-c levels in individuals with T2DM. Both millet type and preparation methods influenced glycemic response. Future well-controlled trials on subjects from multiple ethnicities are needed for generating robust and actionable evidence of the role of millet consumption on metabolic health.

Systemic review registration

International Prospective Register of Systematic Reviews (PROSPERO) CRD42023431941.

查看原文本刊更多论文

谷子食用对成人代谢稳态（血糖控制和脂质谱）的影响：一项系统综述。

目的：系统回顾相关文献，分析谷子食用对成人代谢稳态的影响。方法：通过系统的文献综述，评价食用小米对代谢稳态的影响。使用Science Direct和PubMed数据库检索2025年1月14日之前的文章。使用cochrane - risk -of- bias - assessment量表报告随机对照和交叉研究的质量，而使用非随机干预研究的risk -of- bias -量表报告非随机对照和交叉研究的质量。结果：纳入1项随机对照研究、3项随机交叉研究和2项非随机研究。在2型糖尿病（T2DM）患者中，用谷子、谷子、高粱、玉米、燕麦和玉米制作的杂粮rotis降低了糖化血红蛋白（HbA1c）和低密度脂蛋白胆固醇（LDL-c）水平，谷子剂量降低了餐后血糖水平，用热处理的谷仓谷物制作的食物降低了空腹血糖（FBG）和LDL-c水平。由小米粉和小小米制成的食物降低了糖尿病前期患者的空腹血糖水平。结论：食用小米类食物可改善T2DM患者的血糖反应和LDL-c水平。谷子类型和制备方法均影响血糖反应。未来需要对多种族受试者进行对照良好的试验，以产生强有力的、可操作的证据，证明小米消费对代谢健康的作用。系统评价注册：国际前瞻性系统评价注册（PROSPERO） CRD42023431941。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes & Metabolic Syndrome-Clinical Research & Reviews ENDOCRINOLOGY & METABOLISM-

CiteScore

22.90

自引率

2.00%

发文量

248

审稿时长

51 days

期刊介绍： Diabetes and Metabolic Syndrome: Clinical Research and Reviews is the official journal of DiabetesIndia. It aims to provide a global platform for healthcare professionals, diabetes educators, and other stakeholders to submit their research on diabetes care. Types of Publications: Diabetes and Metabolic Syndrome: Clinical Research and Reviews publishes peer-reviewed original articles, reviews, short communications, case reports, letters to the Editor, and expert comments. Reviews and mini-reviews are particularly welcomed for areas within endocrinology undergoing rapid changes.