Impact of extensive health examination survey screening on quality of life, healthcare use, and mortality: A longitudinal matched cohort study

IF 3.6 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Annals of Epidemiology Pub Date : 2026-01-01 Epub Date: 2025-12-19 DOI:10.1016/j.annepidem.2025.12.008

Ingvild M. Rosenlund MD, PhD , Ellisiv B. Mathiesen Professor, MD, PhD , Unni Ringberg MD, PhD , Liv-Hege Johnsen MD, PhD , Tom Wilsgaard Professor, PhD , Jørgen Isaksen MD, PhD , Tor Ingebrigtsen Professor, MD, PhD

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引用次数: 0

Abstract

Purpose

Widespread use of diagnostic testing in asymptomatic individuals raises ethical concerns. We aimed to investigate whether participation in an extensive health examination survey is associated with psychosocial outcomes, healthcare use, and mortality.

Methods

This longitudinal matched cohort study included 461 participants who underwent comprehensive screening examinations as part of the population-based Tromsø7 Study, including electrocardiogram, carotid artery ultrasound, echocardiography, brain magnetic resonance imaging, and spirometry. Age- and sex-matched controls (n = 461) were drawn from Tromsø7 participants who only underwent limited basic measurements. Health-related quality of life, psychological distress, and health anxiety were assessed at baseline and after 5 years. Data on healthcare utilization and mortality were obtained from national registries.

Results

No significant differences were found in psychosocial outcomes. Healthcare use was largely similar, although screening participants had slightly fewer hospital admissions, 0.23 vs. 0.31 per person-year (95 % CI 0.19, 0.28 vs. 0.25, 0.38). Screening participants also had lower, but non-significant, risk of death compared with controls, hazard ratio 0.69 (95 % CI 0.47, 1.01).

Conclusion

Extensive health examination survey screening was not associated with psychosocial harms, healthcare use or statistically significant differences in mortality. Overall, the findings suggest that participation in such screening is safe.

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广泛健康检查筛查对生活质量、医疗保健使用和死亡率的影响：一项纵向匹配队列研究。

目的：在无症状个体中广泛使用诊断测试引起了伦理问题。我们的目的是调查参与广泛的健康检查调查是否与心理社会结局、医疗保健使用和死亡率有关。方法：这项纵向匹配队列研究纳入了461名参与者，作为基于人群的Tromsø7研究的一部分，他们接受了全面的筛查检查，包括心电图、颈动脉超声、超声心动图、脑磁共振成像和肺活量测定。年龄和性别匹配的对照组（n=461）来自仅接受有限基本测量的Tromsø7参与者。在基线和5年后评估与健康相关的生活质量、心理困扰和健康焦虑。关于医疗保健利用和死亡率的数据来自国家登记处。结果：心理社会结局无显著差异。医疗保健使用大致相似，尽管筛查参与者的住院率略低，每人年0.23比0.31 （95% CI 0.19, 0.28比0.25,0.38）。与对照组相比，筛查参与者的死亡风险也较低，但不显著，风险比为0.69 （95% CI 0.47, 1.01）。结论：广泛的健康检查调查筛查与心理社会伤害、医疗保健使用或死亡率的统计学显著差异无关。总的来说，研究结果表明，参与这种筛查是安全的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Epidemiology 医学-公共卫生、环境卫生与职业卫生

CiteScore

7.40

自引率

1.80%

发文量

207

审稿时长

59 days

期刊介绍： The journal emphasizes the application of epidemiologic methods to issues that affect the distribution and determinants of human illness in diverse contexts. Its primary focus is on chronic and acute conditions of diverse etiologies and of major importance to clinical medicine, public health, and health care delivery.