Trinuclear Manganese(II) Complex Based on Diisopropyl(pyridin-2-ylmethyl)phosphine Oxide

IF 1.1 3区化学 Q4 CHEMISTRY, INORGANIC & NUCLEAR

Russian Journal of Coordination Chemistry Pub Date : 2025-12-18 DOI:10.1134/S1070328425600950

K. R. Enikeeva, D. R. Islamov, S. K. Amerhanova, A. D. Voloshina, I. E. Kolesnikov, E. I. Musina, A. A. Karasik

引用次数: 0

Abstract

A new trinuclear manganese(II) carboxylate complex [Mn₃L₂(OAc)₆] (I), where L is diisopropyl(pyridin-2-ylmethyl)phosphine oxide, was synthesized. The composition of complex I was confirmed by mass spectrometry, IR spectroscopy, and elemental analysis. The crystal structure of the complex was determined by X-ray diffraction (CCDC no. 2447670). The luminescence and cytotoxicity of I were studied in relation to M-HeLa and HuTu80 cancer cell lines and Chang Liver normal cell line It was found that compound I exhibited high cytotoxicity against the HuTu80 cancer cells.

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基于二异丙基（吡啶-2-甲基）氧化膦的三核锰配合物

合成了一种新的三核羧酸锰配合物[Mn3L2(OAc)6] (I)，其中L为二异丙基（吡啶-2-甲基）氧化膦。通过质谱、红外光谱和元素分析证实了配合物I的组成。配合物的晶体结构通过x射线衍射（CCDC no. 1）测定。2447670)。研究了化合物I对M-HeLa、HuTu80癌细胞系和常肝正常细胞系的发光和细胞毒性，发现化合物I对HuTu80癌细胞具有较高的细胞毒性。

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来源期刊

Russian Journal of Coordination Chemistry 化学-无机化学与核化学

CiteScore

2.40

自引率

15.80%

发文量

审稿时长

7.2 months

期刊介绍： Russian Journal of Coordination Chemistry is a journal that publishes reviews, original papers, and short communications on all aspects of theoretical and experimental coordination chemistry. Modern coordination chemistry is an interdisciplinary science that makes a bridge between inorganic, organic, physical, analytical, and biological chemistry.