Challenges of a West African green mamba (Dendroaspis viridis) envenomation in a European urban setting: A case report with quantitative monitoring of neuromuscular transmission

IF 2.8 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Toxicon Pub Date : 2026-03-01 Epub Date: 2025-12-12 DOI:10.1016/j.toxicon.2025.108951
David Eidenbenz , Chiara Scotti , Sébastien Larréché , Jean-Luc Pagani , Pierre-Nicolas Carron
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引用次数: 0

Abstract

Although rare, exotic snakebites are a growing medical concern worldwide, partly due to the rising popularity of exotic pet ownership in high-income countries. Envenomation from family Elapidae snakes may cause severe neurological and local symptoms. Timely antivenom administration is crucial, but often complicated by logistical challenges. We report a case of a West African green mamba (Dendroaspis viridis) envenomation in a 59-year-old male in Switzerland who developed progressive weakness and respiratory failure, associated with swelling of a limb. Quantitative neuromuscular stimulation, also known as a train-of-four monitor, was used to assess neuromuscular transmission after antivenom administration. This case highlights the clinical and organizational challenges following an exotic snakebite.

Abstract Image

西非绿曼巴在欧洲城市环境中的中毒挑战:一份神经肌肉传播定量监测的病例报告。
尽管罕见,但外来蛇咬伤在世界范围内越来越受到医疗关注,部分原因是高收入国家越来越流行饲养外来宠物。蛇科蛇的中毒可引起严重的神经系统和局部症状。及时的抗蛇毒血清注射是至关重要的,但往往由于后勤方面的挑战而变得复杂。我们报告了一例西非绿曼巴(绿曼巴)中毒在59岁的男性在瑞士谁发展出进行性虚弱和呼吸衰竭,与肢体肿胀。定量神经肌肉刺激,也被称为四列监测,用于评估抗蛇毒血清给药后的神经肌肉传递。本病例突出了外来蛇咬伤后的临床和组织挑战。
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来源期刊
Toxicon
Toxicon 医学-毒理学
CiteScore
4.80
自引率
10.70%
发文量
358
审稿时长
68 days
期刊介绍: Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee. Toxicon''s "aims and scope" are to publish: -articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms -papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins -molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins -clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained. -material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems. -articles on the translational application of toxins, for example as drugs and insecticides -epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged. -articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon. -review articles on problems related to toxinology. To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.
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