{"title":"National mortality burden attributable to the unprecedented heatwave in 2022 in China.","authors":"Jian-Xiong Hu, Yu-Lin Zhuo, Guan-Hao He, Jiang-Mei Liu, Yan-Fang Guo, Tian-Tian Li, Wei-Wei Gong, Fang-Fang Zeng, Hai-Lai Duan, Rui-Lin Meng, Chun-Liang Zhou, Yi-Ze Xiao, Min Yu, Biao Huang, Mai-Geng Zhou, Wen-Jun Ma, Tao Liu","doi":"10.1186/s40779-025-00676-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>In 2022, China experienced an unprecedented heatwave event, raising concerns about the health impacts of heatwaves. This study aims to understand the devastating health risk of the exceptional heatwave in 2022 by comparing heatwave-related mortality burden in 2022 with that during 2000-2021.</p><p><strong>Methods: </strong>We collected daily mortality and daily maximum temperature (DMT) during 2006-2017 in 364 locations (counties/districts) of China. Heatwave was defined as an event with 2 or more consecutive days of DMT exceeding the 92.5th percentile. We employed a distributed lag nonlinear model (DLNM) and a meta-analysis to examine the heatwave-mortality association based on the data from 364 counties/districts, and then this association was used to assess the mortality burden attributable to heatwaves during 2000-2022 in 368 cities in China. A percentage change (%) indicator, comparing the 2022 mortality burden to the average value from 2000 to 2021, was further calculated to highlight the severity of heatwaves in 2022.</p><p><strong>Results: </strong>In the past 2 decades, the frequency and intensity of heatwaves in China significantly increased, with the cumulative excessive degree-day increasing to 31,626 in 2022 compared with the annual average value of 13,772 during 2000-2021 across China. In 2022, we observed 62,961 [95% confidence internal (CI) 54,945-70,413] heatwave-related deaths in China, which was much higher than the annual average [35,987 (95% CI 31,252-40,471)] attributable to heatwaves during 2000-2021. The vulnerability groups of heatwave-related mortality in 2022 primarily included patients with cardiovascular diseases [40,567 (95% CI 35,313-45,404)], females [35,876 (95% CI 31,035-41,005)], and people aged over 65 years [56,208 (95% CI 49,023-62,864)]; and greater heatwave-related mortality was found in eastern-central China. The attributable fraction (AF) of heatwave-related deaths increased from an annual average of 11.01‰ (95% CI 9.56-12.38) during 2000-2021 to 18.11‰ (95% CI 15.80-20.25) in 2022 with 64.43% increment (95% CI 38.10-93.78), and the increase rates were greater in Xizang Autonomous Region (159.77%, 95% CI 12.84-477.87) and Sichuan Province (133.64%, 95% CI 3.84-416.61).</p><p><strong>Conclusions: </strong>This study indicated that the frequency and intensity of heatwaves significantly increased in the past 2 decades in China, and the 2022 heatwaves were linked to a substantial mortality burden in China, with significant population and regional heterogeneity. Our findings underscore the need for developing comprehensive heat adaptation plans in the context of rapid aging and ongoing global warming.</p>","PeriodicalId":18581,"journal":{"name":"Military Medical Research","volume":"12 1","pages":"92"},"PeriodicalIF":29.0000,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12703895/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Military Medical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s40779-025-00676-2","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: In 2022, China experienced an unprecedented heatwave event, raising concerns about the health impacts of heatwaves. This study aims to understand the devastating health risk of the exceptional heatwave in 2022 by comparing heatwave-related mortality burden in 2022 with that during 2000-2021.
Methods: We collected daily mortality and daily maximum temperature (DMT) during 2006-2017 in 364 locations (counties/districts) of China. Heatwave was defined as an event with 2 or more consecutive days of DMT exceeding the 92.5th percentile. We employed a distributed lag nonlinear model (DLNM) and a meta-analysis to examine the heatwave-mortality association based on the data from 364 counties/districts, and then this association was used to assess the mortality burden attributable to heatwaves during 2000-2022 in 368 cities in China. A percentage change (%) indicator, comparing the 2022 mortality burden to the average value from 2000 to 2021, was further calculated to highlight the severity of heatwaves in 2022.
Results: In the past 2 decades, the frequency and intensity of heatwaves in China significantly increased, with the cumulative excessive degree-day increasing to 31,626 in 2022 compared with the annual average value of 13,772 during 2000-2021 across China. In 2022, we observed 62,961 [95% confidence internal (CI) 54,945-70,413] heatwave-related deaths in China, which was much higher than the annual average [35,987 (95% CI 31,252-40,471)] attributable to heatwaves during 2000-2021. The vulnerability groups of heatwave-related mortality in 2022 primarily included patients with cardiovascular diseases [40,567 (95% CI 35,313-45,404)], females [35,876 (95% CI 31,035-41,005)], and people aged over 65 years [56,208 (95% CI 49,023-62,864)]; and greater heatwave-related mortality was found in eastern-central China. The attributable fraction (AF) of heatwave-related deaths increased from an annual average of 11.01‰ (95% CI 9.56-12.38) during 2000-2021 to 18.11‰ (95% CI 15.80-20.25) in 2022 with 64.43% increment (95% CI 38.10-93.78), and the increase rates were greater in Xizang Autonomous Region (159.77%, 95% CI 12.84-477.87) and Sichuan Province (133.64%, 95% CI 3.84-416.61).
Conclusions: This study indicated that the frequency and intensity of heatwaves significantly increased in the past 2 decades in China, and the 2022 heatwaves were linked to a substantial mortality burden in China, with significant population and regional heterogeneity. Our findings underscore the need for developing comprehensive heat adaptation plans in the context of rapid aging and ongoing global warming.
背景:2022年,中国经历了前所未有的热浪事件,引发了人们对热浪对健康影响的担忧。本研究旨在通过比较2022年与2000-2021年热浪相关的死亡率负担,了解2022年异常热浪带来的破坏性健康风险。方法:收集2006-2017年中国364个地点(县/区)的日死亡率和日最高气温(DMT)。热浪被定义为连续2天或更长时间的DMT超过92.5个百分位数的事件。基于364个县(区)的数据,采用分布滞后非线性模型(DLNM)和meta分析对热浪与死亡率的关联进行了检验,并利用这种关联对2000-2022年中国368个城市的热浪死亡率负担进行了评估。进一步计算了百分比变化指标,将2022年死亡率负担与2000年至2021年的平均值进行比较,以突出2022年热浪的严重程度。结果:近20 a来,中国热浪发生的频率和强度均显著增加,累计过度日数从2000-2021年的13772增加到2022年的31626;在2022年,我们观察到中国与热浪相关的死亡人数为62,961人[95%置信区间(CI) 54,945-70,413],远高于2000-2021年期间热浪造成的年平均死亡人数[35,987人(95% CI 31,252-40,471)]。2022年热浪相关死亡率的易感人群主要包括心血管疾病患者[40,567 (95% CI 35,313-45,404)]、女性[35,876 (95% CI 31,035-41,005)]和65岁以上人群[56,208 (95% CI 49,023-62,864)];中国中东部地区与热浪相关的死亡率更高。热浪相关死亡归因分数(AF)从2000-2021年的年均11.01‰(95% CI 9.56 ~ 12.38)增加到2022年的18.11‰(95% CI 15.80 ~ 20.25),增幅为64.43% (95% CI 38.10 ~ 93.78),其中西藏自治区(159.77%,95% CI 12.84 ~ 477.87)和四川省(133.64%,95% CI 3.84 ~ 416.61)增幅较大。结论:该研究表明,在过去20年中,中国热浪的频率和强度显著增加,2022年的热浪与中国的大量死亡负担有关,具有显著的人口和区域异质性。我们的研究结果强调了在快速老龄化和持续全球变暖的背景下制定综合热适应计划的必要性。
期刊介绍:
Military Medical Research is an open-access, peer-reviewed journal that aims to share the most up-to-date evidence and innovative discoveries in a wide range of fields, including basic and clinical sciences, translational research, precision medicine, emerging interdisciplinary subjects, and advanced technologies. Our primary focus is on modern military medicine; however, we also encourage submissions from other related areas. This includes, but is not limited to, basic medical research with the potential for translation into practice, as well as clinical research that could impact medical care both in times of warfare and during peacetime military operations.