{"title":"Global, Regional, and National Burden and Trends of Maternal Hypertensive Disorders from 1990 to 2021: A Population-Based Study.","authors":"Li Yang, Wenting Xu","doi":"10.2147/IJWH.S550876","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to comprehensively assess the global, regional, and national burden and trends of maternal hypertensive disorders (MHD) from 1990 to 2021.</p><p><strong>Methods: </strong>By analyzing MHD data from 1999 to 2021, age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years (ASDR) were screened, and estimated annual percentage change (EAPC) was calculated. This study used joinpoint regression analysis to examine trends during the period. This study investigated the differences in the burden of MHD among different Socio-demographic Index (SDI) regions through health inequalities analysis. Finally, we used the Bayesian age-period-cohort (BAPC) model to predict the trend in incidence, mortality, and DALYs rates of MHD over the next 25 years.</p><p><strong>Results: </strong>The results showed that in 2021, the global ASIR, ASMR and ASDR were 461.94, 0.97 and 63.47, respectively (per 100000 population). From 1990 to 2021, the EAPC results showed a decreasing trend in the global ASIR, ASMR, and ASDR of MHD. The joinpoint regression results showed that the global ASIR, ASMR, and ASDR of MHD showed an overall downward trend from 1990 to 2021. Countries with lower SDI levels bore a higher burden. The predicted incidence, mortality, and DALYs rates of MHD for the next 25 years are both showing a downward trend.</p><p><strong>Conclusion: </strong>The global ASIR, ASMR, and ASDR of MHD were all showing a downward trend from 1990 to 2021. However, this study found that Africa and low SDI regions bore a significant burden. The disparity in economic development could lead to an exacerbation of health inequalities. Therefore, it was emphasized that relevant public health policies should be formulated for African and low SDI regions. Medical staff should raise awareness of the risks of MHD and actively handle emergencies caused by MHD to reduce mortality, and DALYs rates and alleviate social burden.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"5237-5248"},"PeriodicalIF":2.6000,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12695708/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Women's Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/IJWH.S550876","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: This study aimed to comprehensively assess the global, regional, and national burden and trends of maternal hypertensive disorders (MHD) from 1990 to 2021.
Methods: By analyzing MHD data from 1999 to 2021, age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years (ASDR) were screened, and estimated annual percentage change (EAPC) was calculated. This study used joinpoint regression analysis to examine trends during the period. This study investigated the differences in the burden of MHD among different Socio-demographic Index (SDI) regions through health inequalities analysis. Finally, we used the Bayesian age-period-cohort (BAPC) model to predict the trend in incidence, mortality, and DALYs rates of MHD over the next 25 years.
Results: The results showed that in 2021, the global ASIR, ASMR and ASDR were 461.94, 0.97 and 63.47, respectively (per 100000 population). From 1990 to 2021, the EAPC results showed a decreasing trend in the global ASIR, ASMR, and ASDR of MHD. The joinpoint regression results showed that the global ASIR, ASMR, and ASDR of MHD showed an overall downward trend from 1990 to 2021. Countries with lower SDI levels bore a higher burden. The predicted incidence, mortality, and DALYs rates of MHD for the next 25 years are both showing a downward trend.
Conclusion: The global ASIR, ASMR, and ASDR of MHD were all showing a downward trend from 1990 to 2021. However, this study found that Africa and low SDI regions bore a significant burden. The disparity in economic development could lead to an exacerbation of health inequalities. Therefore, it was emphasized that relevant public health policies should be formulated for African and low SDI regions. Medical staff should raise awareness of the risks of MHD and actively handle emergencies caused by MHD to reduce mortality, and DALYs rates and alleviate social burden.
期刊介绍：
International Journal of Women''s Health is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of women''s healthcare including gynecology, obstetrics, and breast cancer. Subject areas include: Chronic conditions including cancers of various organs specific and not specific to women Migraine, headaches, arthritis, osteoporosis Endocrine and autoimmune syndromes - asthma, multiple sclerosis, lupus, diabetes Sexual and reproductive health including fertility patterns and emerging technologies to address infertility Infectious disease with chronic sequelae including HIV/AIDS, HPV, PID, and other STDs Psychological and psychosocial conditions - depression across the life span, substance abuse, domestic violence Health maintenance among aging females - factors affecting the quality of life including physical, social and mental issues Avenues for health promotion and disease prevention across the life span Male vs female incidence comparisons for conditions that affect both genders.
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