Preparation and characterization of ultrasound-mediated Ocimum basilicum L. essential oil nanoemulsion and its application in meat preservation

IF 10.2 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry Pub Date : 2026-01-01 Epub Date: 2025-12-13 DOI:10.1016/j.ultsonch.2025.107721

Yue Wang , Weixuan Pan , Xiangjun Yang , Ende Song , Hui Zhang , Yiming Liu , Kehui Wang , Huiwen Wu , Qi Liu

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Abstract

In this study, a stable basil oil nanoemulsion was prepared by emulsifier-assisted ultrasonication. The optimized formulation exhibited excellent physical stability under ambient, refrigerated (4 °C), and heated (55 °C) conditions. It demonstrated strong antibacterial activity against E. coli and S. aureus, inducing membrane disruption and oxidative stress, as evidenced by elevated ROS and MDA levels. The nanoemulsion also showed significant antioxidant capacity, scavenging 95 % of DPPH and 86 % of ABTS radicals and achieving a FRAP value of 14.6 µmol/g at 200 µg/mL. Cytotoxicity analysis confirmed high biocompatibility, with cell viability exceeding 83 % in L02 and BEAS-2B cells at 16 mg/mL. When applied to beef packaging, the nanoemulsion effectively maintained pH, reduced microbial counts, and suppressed TVB-N accumulation, thereby prolonging meat freshness. These findings highlight its potential as a multifunctional preservative for food and biomedical applications.

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超声介导罗勒精油纳米乳的制备、表征及其在肉类保鲜中的应用

本研究采用乳化剂辅助超声法制备了稳定的罗勒油纳米乳。优化后的配方在室温、冷藏（4 °C）和加热（55 °C）条件下均表现出优异的物理稳定性。它对大肠杆菌和金黄色葡萄球菌具有很强的抗菌活性，可以诱导膜破坏和氧化应激，这可以通过提高ROS和MDA水平来证明。纳米乳还显示出显著的抗氧化能力，清除95 %的DPPH和86 %的ABTS自由基，在200 µg/mL时达到14.6 µmol/g的FRAP值。细胞毒性分析证实了高的生物相容性，在16 mg/mL浓度下，L02和BEAS-2B细胞的细胞存活率超过83 %。当应用于牛肉包装时，纳米乳有效地维持了pH值，减少了微生物数量，抑制了TVB-N的积累，从而延长了肉类的新鲜度。这些发现突出了其作为食品和生物医学用途的多功能防腐剂的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ultrasonics Sonochemistry 化学-化学综合

CiteScore

15.80

自引率

11.90%

发文量

361

审稿时长

59 days

期刊介绍： Ultrasonics Sonochemistry stands as a premier international journal dedicated to the publication of high-quality research articles primarily focusing on chemical reactions and reactors induced by ultrasonic waves, known as sonochemistry. Beyond chemical reactions, the journal also welcomes contributions related to cavitation-induced events and processing, including sonoluminescence, and the transformation of materials on chemical, physical, and biological levels. Since its inception in 1994, Ultrasonics Sonochemistry has consistently maintained a top ranking in the "Acoustics" category, reflecting its esteemed reputation in the field. The journal publishes exceptional papers covering various areas of ultrasonics and sonochemistry. Its contributions are highly regarded by both academia and industry stakeholders, demonstrating its relevance and impact in advancing research and innovation.

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