Prognostic Value of HALP Score in Predicting Contrast-Induced Acute Kidney Injury in Elderly STEMI Patients.

IF 2.7 3区医学 Q2 PERIPHERAL VASCULAR DISEASE

Angiology Pub Date : 2026-11-01 Epub Date: 2025-12-12 DOI:10.1177/00033197251395839

Macit Kalçık, Emrah Bayam, Regayip Zehir

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引用次数: 0

Abstract

Contrast-induced acute kidney injury (CI-AKI) is a common complication in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI), particularly in the elderly who are more vulnerable due to renal impairment, comorbidities, malnutrition, and chronic inflammation. The hemoglobin, albumin, lymphocyte, and platelet (HALP) score has been proposed as a biomarker reflecting nutritional and inflammatory status, but its role in predicting CI-AKI in elderly STEMI patients is unclear. This retrospective study included 588 elderly (≥65 years) STEMI patients treated with pPCI between August 2019 and December 2024. CI-AKI occurred in 70 patients (11.9%), who were older and had higher rates of diabetes mellitus (DM), hypertension, and chronic kidney disease, along with lower glomerular filtration rate (GFR), left ventricular ejection fraction (LVEF), and HALP score. The mean HALP score was significantly lower in patients with CI-AKI (2.68 [2.33-3.32] vs 3.85 [2.68-5.37], P < .001). In multivariate analysis, older age, DM, lower LVEF, higher contrast volume, and lower HALP score independently predicted CI-AKI. A HALP score <2.7 predicted CI-AKI with 75% sensitivity and 55% specificity (Area Under the Curve: 0.698). The HALP score provides an accessible, independent predictor of CI-AKI in elderly STEMI patients, enabling improved early risk stratification.

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HALP评分预测老年STEMI患者造影剂性急性肾损伤的预后价值。

对比剂诱导的急性肾损伤（CI-AKI）是st段抬高型心肌梗死（STEMI）患者接受原发性经皮冠状动脉介入治疗（pPCI）的常见并发症，特别是在老年人中，由于肾脏损害、合并症、营养不良和慢性炎症更容易发生。血红蛋白、白蛋白、淋巴细胞和血小板（HALP）评分已被提出作为反映营养和炎症状态的生物标志物，但其在预测老年STEMI患者CI-AKI中的作用尚不清楚。该回顾性研究纳入了2019年8月至2024年12月期间接受pPCI治疗的588例老年（≥65岁）STEMI患者。CI-AKI发生在70例（11.9%）患者中，这些患者年龄较大，糖尿病（DM）、高血压和慢性肾脏疾病发生率较高，肾小球滤过率（GFR）、左心室射血分数（LVEF）和HALP评分均较低。CI-AKI患者的平均HALP评分显著低于前者(2.68 [2.33-3.32]vs . 3.85 [2.68-5.37]， P

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Angiology 医学-外周血管病

CiteScore

5.50

自引率

14.30%

发文量

180

审稿时长

6-12 weeks

期刊介绍： A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days