Inflammatory Dietary Pattern Associated With Metabolic Biomarkers, Blood Pressure and Anthropometric Indicators in Brazilian Adolescents

IF 2.5 3区医学 Q1 PEDIATRICS

Pediatric Obesity Pub Date : 2025-12-10 DOI:10.1111/ijpo.70079

Luana S. Blaudt, Taís de S. Lopes, Amanda de M. Souza, Geisa Gabriela B. Rodrigues, Iuna A. Alves, Rosangela A. Pereira

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引用次数: 0

Abstract

Background

Diet may influence the subclinical inflammatory responses related to metabolic disorders.

Objective

To identify a dietary pattern associated with inflammatory biomarkers and to evaluate its association with metabolic, clinical and anthropometric indicators in Brazilian adolescents.

Methods

Data from Brazilian adolescents aged 12–17 years participating in the Study of Cardiovascular Risk in Adolescents (ERICA, 2013–2014) were analysed. Dietary intake was assessed using a 24-h dietary recall. A dietary pattern was derived using the Partial Least Squares regression in a subset (n = 3703) with C-reactive protein and adiponectin as intermediate variables and retaining food groups with factor loadings ≥ |0.15|. Associations between the pro-inflammatory dietary pattern and anthropometric indicators and metabolic biomarkers were examined in a subsample of adolescents (n = 36 956) using crude and adjusted multiple linear regression models.

Results

The pro-inflammatory dietary pattern was characterised by positive loadings for soft drinks, cakes, cheese, fats, pasta, snacks, sweets and bread, and with negative loadings for rice, milk-based dishes, poultry, fish and beans. The mean inflammatory dietary pattern score was 0.05 overall, and higher for girls (0.08) than boys (0.03). Significant associations (p < 0.05) were found between the pro-inflammatory dietary pattern and increased BMI (β = 0.07 kg/m²), fasting blood glucose (β = 0.20 mg/dL) and HOMA-IR (β = 0.03), after adjusting for sex, age, school type, diet report quality and daily energy intake.

Conclusions

Among Brazilian adolescents, a pro-inflammatory dietary pattern was associated with higher body weight, fasting glucose and insulin resistance.

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炎症性饮食模式与巴西青少年代谢生物标志物、血压和人体测量指标相关

饮食可能影响与代谢紊乱相关的亚临床炎症反应。目的确定与炎症生物标志物相关的饮食模式，并评估其与巴西青少年代谢、临床和人体测量指标的关系。方法对参与青少年心血管风险研究（ERICA, 2013-2014）的12-17岁巴西青少年的数据进行分析。采用24小时饮食回忆法评估膳食摄入量。以c反应蛋白和脂联素为中间变量，保留因子负荷≥| - 0.15|的食物组，采用偏最小二乘回归法对一个子集（n = 3703）进行饮食模式推导。在青少年亚样本（n = 36956）中，使用粗糙和调整后的多元线性回归模型检验了促炎饮食模式与人体测量指标和代谢生物标志物之间的关系。结果：促炎饮食模式的特点是软饮料、蛋糕、奶酪、脂肪、面食、零食、糖果和面包的积极负荷，而大米、牛奶类菜肴、家禽、鱼和豆类的消极负荷。炎性饮食模式平均评分为0.05，女孩（0.08）高于男孩（0.03）。在调整性别、年龄、学校类型、饮食报告质量和每日能量摄入后，促炎饮食模式与BMI （β = 0.07 kg/m2）、空腹血糖（β = 0.20 mg/dL）和HOMA-IR （β = 0.03）升高存在显著相关（p < 0.05）。结论：在巴西青少年中，促炎饮食模式与较高的体重、空腹血糖和胰岛素抵抗有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Obesity PEDIATRICS-

CiteScore

7.30

自引率

5.30%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Pediatric Obesity is a peer-reviewed, monthly journal devoted to research into obesity during childhood and adolescence. The topic is currently at the centre of intense interest in the scientific community, and is of increasing concern to health policy-makers and the public at large. Pediatric Obesity has established itself as the leading journal for high quality papers in this field, including, but not limited to, the following: Genetic, molecular, biochemical and physiological aspects of obesity – basic, applied and clinical studies relating to mechanisms of the development of obesity throughout the life course and the consequent effects of obesity on health outcomes Metabolic consequences of child and adolescent obesity Epidemiological and population-based studies of child and adolescent overweight and obesity Measurement and diagnostic issues in assessing child and adolescent adiposity, physical activity and nutrition Clinical management of children and adolescents with obesity including studies of treatment and prevention Co-morbidities linked to child and adolescent obesity – mechanisms, assessment, and treatment Life-cycle factors eg familial, intrauterine and developmental aspects of child and adolescent obesity Nutrition security and the "double burden" of obesity and malnutrition Health promotion strategies around the issues of obesity, nutrition and physical activity in children and adolescents Community and public health measures to prevent overweight and obesity in children and adolescents.