Meta-analysis of risk factors for pulmonary infection in patients with cervical spinal cord injury.

IF 1.3 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Spinal Cord Medicine Pub Date : 2026-09-01 Epub Date: 2025-12-08 DOI:10.1080/10790268.2025.2588899

Yichen Gong, Ning Li

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引用次数: 0

Abstract

Objective: To conduct a meta-analysis of the literature to summarize the risk factors for pulmonary infection in patients with cervical spinal cord injury.

Methods: Computer-based searches were performed in CNKI, CBM, Wanfang Database, VIP Series Databases, The Cochrane Library, WOS, PubMed, Springer Link, EBSCO, MEDLINE and other databases. The time frame was from January 1, 2000 to April 1, 2025. Case-control studies and cohort studies related publications were searched according to subject terms and free words. According to inclusion and exclusion criteria, 7 publications were identified, and finally meta-analysis was performed on them by Review Manager 5.3 software.

Results: Seven publications met the inclusion criteria, with a total of 912 cases and 742 controls. The results of meta-analysis showed that the risk factors for pulmonary infection in patients with cervical spinal cord injury were: American Spinal Injury Association (ASIA) Impairment Scale (AIS) - AIS A and AIS B (OR: 3.90, 95% CI: 2.74-5.53), high-level injury (OR: 2.73, 95% CI: 1.69-4.40), hormone shock therapy (OR: 4.14, 95% CI: 2.58-6.62), smoking history (OR = 2.34, 95% CI: 1.54-3.55), operation time (P < 0.00001, I² = 96%), hypoalbuminemia (P < 0.00001, I² = 96%), and age (P < 0.00001, I² = 95%).

Conclusion: AIS A and B, high-level injury, hormone shock therapy and smoking history are risk factors for pulmonary infection in patients with cervical spinal cord injury. Controlling the above factors can effectively reduce the incidence of pulmonary infection in patients with cervical spinal cord injury.

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颈脊髓损伤患者肺部感染危险因素荟萃分析。

目的：通过文献荟萃分析，总结颈脊髓损伤患者肺部感染的危险因素。方法：计算机检索CNKI、CBM、万方数据库、VIP系列数据库、The Cochrane Library、WOS、PubMed、施普林格Link、EBSCO、MEDLINE等数据库。时间范围是从2000年1月1日到2025年4月1日。根据主题词和自由词检索病例对照研究和队列研究相关出版物。根据纳入和排除标准筛选出7篇文献，最后使用Review Manager 5.3软件对其进行meta分析。结果：7篇文献符合纳入标准，共纳入病例912例，对照742例。荟萃分析的结果表明,肺部感染的危险因素在颈脊髓损伤患者:美国脊髓损伤学会(亚洲)障碍量表(AIS)——AIS和AIS B (OR: 3.90, 95% CI: 2.74—-5.53),高层受伤(OR: 2.73, 95% CI: 1.69—-4.40),激素冲击疗法(OR: 4.14, 95% CI: 2.58—-6.62),吸烟史(OR = 2.34, 95% CI: 1.54—-3.55),操作时间(P I2 = 96%),低白蛋白血症(P I2 = 96%),和年龄(P I2 = 95%)。结论：AIS A、B级、高水平损伤、激素休克治疗和吸烟史是颈脊髓损伤患者肺部感染的危险因素。控制上述因素可有效降低颈脊髓损伤患者肺部感染的发生率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Spinal Cord Medicine 医学-临床神经学

CiteScore

4.20

自引率

5.90%

发文量

101

审稿时长

6-12 weeks

期刊介绍： For more than three decades, The Journal of Spinal Cord Medicine has reflected the evolution of the field of spinal cord medicine. From its inception as a newsletter for physicians striving to provide the best of care, JSCM has matured into an international journal that serves professionals from all disciplines—medicine, nursing, therapy, engineering, psychology and social work.