Prolonged Clinical Course and Unexpected Outcome of Postinfectious Glomerulonephritis in an 11-Year-Old Boy.

IF 0.5 Q4 UROLOGY & NEPHROLOGY
Sufia Husain, Raghad Bokhari, Tariq AlJohani, Adi Alherbish, Syed Amir Ahmad
{"title":"Prolonged Clinical Course and Unexpected Outcome of Postinfectious Glomerulonephritis in an 11-Year-Old Boy.","authors":"Sufia Husain, Raghad Bokhari, Tariq AlJohani, Adi Alherbish, Syed Amir Ahmad","doi":"10.4103/sjkdt.sjkdt_483_21","DOIUrl":null,"url":null,"abstract":"<p><p>Postinfectious glomerulonephritis (PIGN) is one of the most common causes of acute kidney injury in children worldwide. In most cases, there is complete clinical and morphological recovery. Rarely, patients present with persistent abnormal renal function for a few months or years after an episode of PIGN, some even progressing to renal failure. Here, we describe a case of an 11-year-old boy with biopsy-diagnosed PIGN, demonstrating persistent proteinuria, hematuria, and hypertension even 1 year after being treated for PIGN. A second follow-up biopsy showed chronic glomerulopathy in the form of focal and segmental glomerulosclerosis (FSGS) and mesangial hypercellularity. The journey of this patient from PIGN to FSGS is detailed in this case report.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"35 1-6","pages":"121-126"},"PeriodicalIF":0.5000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Saudi Journal of Kidney Diseases and Transplantation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/sjkdt.sjkdt_483_21","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/12/6 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Postinfectious glomerulonephritis (PIGN) is one of the most common causes of acute kidney injury in children worldwide. In most cases, there is complete clinical and morphological recovery. Rarely, patients present with persistent abnormal renal function for a few months or years after an episode of PIGN, some even progressing to renal failure. Here, we describe a case of an 11-year-old boy with biopsy-diagnosed PIGN, demonstrating persistent proteinuria, hematuria, and hypertension even 1 year after being treated for PIGN. A second follow-up biopsy showed chronic glomerulopathy in the form of focal and segmental glomerulosclerosis (FSGS) and mesangial hypercellularity. The journey of this patient from PIGN to FSGS is detailed in this case report.

1例11岁男童感染后肾小球肾炎的临床病程延长及意外结局。
感染后肾小球肾炎(PIGN)是全球儿童急性肾损伤最常见的原因之一。在大多数情况下,有完全的临床和形态恢复。罕见的是,患者在PIGN发作后几个月或几年持续出现肾功能异常,有些甚至进展为肾功能衰竭。在这里,我们描述了一个11岁的男孩,活检诊断为PIGN,表现出持续蛋白尿,血尿和高血压,甚至在接受PIGN治疗一年后。第二次随访活检显示慢性肾小球病变,表现为局灶性和节段性肾小球硬化(FSGS)和系膜细胞增多。本病例报告详细描述了该患者从PIGN到FSGS的过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.00
自引率
0.00%
发文量
49
审稿时长
53 weeks
期刊介绍: Saudi Journal of Kidney Diseases and Transplantation (SJKDT, ISSN 1319-2442) is the official publication of the Saudi Center for Organ Transplantation, Riyadh, Saudi Arabia. It is published six times a year. SJKDT publishes peer-reviewed original research work and review papers related to kidney diseases, urinary tract, renal replacement therapies, and transplantation. The journal publishes original papers and reviews on cell therapy and islet transplantation, clinical transplantation, experimental transplantation, immunobiology and genomics and xenotransplantation related to the kidney. The journal also publishes short communications, case studies, letters to the editors, an annotated bibliography and a column on news and views.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书