Neuroform Atlas single-stent coiling for wide-neck MCA bifurcation aneurysms: a retrospective single-centre case series

Q3 Medicine
Zhiyong Huang , Bing Huang , Jianlei An , Hao Sun , Shuchao Chen , Jiaxi Liu , Dejiang Guo , Lei Liu
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引用次数: 0

Abstract

Background

Wide-neck aneurysms at the middle cerebral artery (MCA) bifurcation pose a recognized challenge for endovascular treatment. Y- or X-stent configurations can reconstruct the bifurcation but increase procedural complexity and complication risk. The Neuroform Atlas is a low-profile, open-cell stent that allows single-stent neck reconstruction through 0.0165-inch microcatheters. Evidence on its performance in Chinese patients remains limited.

Methods

We conducted a retrospective, single-centre case series of 15 consecutive patients with wide-neck MCA bifurcation aneurysms treated with Neuroform Atlas stent-assisted coiling at the Aviation General Hospital (Beijing, China) between October 2023 and February 2025. Inclusion criteria were aneurysm neck >4 ​mm or dome-to-neck ratio <1.5, age 18–75 years and ability to comply with follow-up; both ruptured (Hunt–Hess I–III) and unruptured aneurysms were included. Fourteen aneurysms were treated with a single stent and one required Y-stenting. The primary endpoint was complete occlusion (Raymond grade I) at 6-month angiographic follow-up; secondary endpoints included periprocedural thromboembolic or haemorrhagic events, functional outcome measured by the modified Rankin Scale (mRS) and the need for retreatment. Data were summarised descriptively.

Results

Patients had a median age of 61 years (range 30–75 years) and were predominantly female (73 ​%). Aneurysms had a median neck width of 4.2 ​mm and mean maximum diameter of 5.16 ​mm; 40 ​% presented with subarachnoid haemorrhage. Technical success was 100 ​%, with 14/15 aneurysms treated using a single stent. Immediate or follow-up angiography showed Raymond grade I occlusion in all cases. No periprocedural thromboembolic or haemorrhagic events were observed, all patients achieved mRS ≤2 ​at last follow-up, and no recurrences or retreatments were required.

Conclusions

In this small retrospective series, Neuroform Atlas single-stent-assisted coiling was feasible and achieved complete occlusion with no procedure-related complications in wide-neck MCA bifurcation aneurysms. These preliminary results suggest the approach may offer a safe and effective alternative to complex dual-stenting techniques, but larger prospective studies with control groups are needed to confirm its generalizability.
神经形态Atlas单支架卷绕治疗宽颈MCA分岔动脉瘤:回顾性单中心病例系列
背景:大脑中动脉(MCA)分叉处的宽颈动脉瘤是血管内治疗的一个公认的挑战。Y型或x型支架可以重建分叉,但增加了手术的复杂性和并发症的风险。Neuroform Atlas是一种低调的开细胞支架,允许通过0.0165英寸的微导管进行单支架颈部重建。关于其在中国患者中的疗效的证据仍然有限。方法:我们对2023年10月至2025年2月在中国北京航空总医院接受神经形态Atlas支架辅助卷曲治疗的连续15例宽颈MCA分叉动脉瘤患者进行回顾性、单中心病例系列研究。纳入标准为动脉瘤颈≥4mm或颈圆比≥1.5,年龄18-75岁,有随访能力;包括破裂动脉瘤(Hunt-Hess I-III)和未破裂动脉瘤。14个动脉瘤用一个支架治疗,1个需要y型支架。在6个月的血管造影随访中,主要终点是完全闭塞(雷蒙德I级);次要终点包括围手术期血栓栓塞或出血事件、用改良Rankin量表(mRS)测量的功能结局以及是否需要再治疗。对数据进行描述性总结。结果患者年龄中位数为61岁(30 ~ 75岁),以女性为主(73%)。动脉瘤中位颈宽4.2 mm,平均最大直径5.16 mm;40%表现为蛛网膜下腔出血。技术成功率为100%,其中14/15个动脉瘤使用单一支架治疗。立即或随访血管造影显示所有病例雷蒙德I级闭塞。未观察到围手术期血栓栓塞或出血事件,所有患者在最后随访时均达到mRS≤2,无复发或再治疗。结论在这个小型回顾性研究中,神经形态寰椎单支架辅助卷绕术是可行的,并且在无手术相关并发症的情况下实现了宽颈MCA分叉动脉瘤的完全闭塞。这些初步结果表明,该方法可能为复杂的双支架置入技术提供了一种安全有效的替代方法,但需要更大规模的对照组前瞻性研究来证实其普遍性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medicine in Novel Technology and Devices
Medicine in Novel Technology and Devices Medicine-Medicine (miscellaneous)
CiteScore
3.00
自引率
0.00%
发文量
74
审稿时长
64 days
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