Quantitative intraoperative lateral spread response amplitudes in hemifacial Spasm: Associations with vascular burden

IF 3.4 3区医学 Q1 CLINICAL NEUROLOGY

Clinical Neurophysiology Pub Date : 2026-01-01 Epub Date: 2025-12-01 DOI:10.1016/j.clinph.2025.2111466

Minsoo Kim , Soung Wook Park , Hyun Seok Lee , Sang-Ku Park , Kwan Park

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引用次数: 0

Abstract

Objective

To determine whether intraoperative lateral spread response (LSR) amplitudes reflect vascular burden and configuration in hemifacial spasm.

Methods

We retrospectively reviewed consecutive microvascular decompressions at a single center. LSR I (mentalis) and LSR II (frontalis) were recorded using a standardized protocol. The primary exposure was arterial vessel count (single vs. multiple); vein-only cases were exploratory owing to imbalance. Amplitudes and derived indices (I/II ratio, I–II difference) were compared using variance-aware parametric and nonparametric tests.

Results

LSRs were obtained in most patients. LSR I exceeded LSR II with a significant paired effect. Arterial burden showed a graded pattern in LSR I, with higher amplitudes in multiple-vessel compression; however, differences across vessels counts were not significant after adjustment. No differences were observed for LSR II. Derived indices better reflected vascular burden, showing significant contrasts where raw amplitudes did not, including single-versus-multiple comparisons. Vein-only cases appeared lower but remained exploratory.

Conclusions

Intraoperative LSR amplitudes, especially at the mentalis muscle, reflect arterial burden, and derived indices improve discrimination. Findings support amplitude-based monitoring, with multicenter studies needed to confirm underlying mechanisms and predictive utility.

Significance

LSR monitoring offers a practical marker of vascular burden, potentially guiding surgical decisions and improving outcomes.

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术中面肌痉挛的定量侧展反应振幅：与血管负荷的关系

目的探讨术中侧张反应（LSR）振幅是否反映了面肌痉挛患者的血管负荷和形态。方法回顾性分析单中心连续微血管减压术。LSR I（颏部）和LSR II（额部）采用标准化记录。主要暴露是动脉血管计数（单个vs多个）；由于不平衡，单纯静脉病例是探索性的。振幅和衍生指数（I/II比率，I - II差异）通过方差感知参数和非参数检验进行比较。结果大多数患者均获得slrs。LSR I超过LSR II，具有显著的配对效应。动脉负荷在LSR I中呈分级模式，在多血管受压时呈较高振幅；然而，调整后血管计数差异不显著。LSR II没有观察到差异。衍生指数更好地反映了血管负荷，在原始振幅没有的情况下显示出显著的对比，包括单次与多次比较。只有静脉的病例似乎较低，但仍是探索性的。结论术中LSR波幅，尤其是颏肌处的LSR波幅，反映了动脉负荷，其衍生指标有助于鉴别。研究结果支持基于振幅的监测，需要多中心研究来确认潜在的机制和预测效用。elsr监测提供了血管负荷的实用标记物，可能指导手术决策和改善预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neurophysiology 医学-临床神经学

CiteScore

8.70

自引率

6.40%

发文量

932

审稿时长

59 days

期刊介绍： As of January 1999, The journal Electroencephalography and Clinical Neurophysiology, and its two sections Electromyography and Motor Control and Evoked Potentials have amalgamated to become this journal - Clinical Neurophysiology. Clinical Neurophysiology is the official journal of the International Federation of Clinical Neurophysiology, the Brazilian Society of Clinical Neurophysiology, the Czech Society of Clinical Neurophysiology, the Italian Clinical Neurophysiology Society and the International Society of Intraoperative Neurophysiology.The journal is dedicated to fostering research and disseminating information on all aspects of both normal and abnormal functioning of the nervous system. The key aim of the publication is to disseminate scholarly reports on the pathophysiology underlying diseases of the central and peripheral nervous system of human patients. Clinical trials that use neurophysiological measures to document change are encouraged, as are manuscripts reporting data on integrated neuroimaging of central nervous function including, but not limited to, functional MRI, MEG, EEG, PET and other neuroimaging modalities.