Burn injuries in the Asia-Pacific region: Use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) for wound bed preparation in children and adults.
Harikrishna Kr Nair, Pornprom Muangman, Yan Liu, Kerrie Coleman, Wipawee Kanpuan, Mohd Shahrul Suondoh, Salmi Mohamed Sukur, Anchan Ketmek, Suttipong Tianwattanatada, Suchada Kittidacha, Orapin Taengthet, Wen Liang Wang, Min Gao, Zong Qi Yin, Yi Dou, Jia Jun Zhu, Chenlu Song, Gai Zhang, Xuechuan Li, Huizhong Yang, Duong Van Phu, Nguyen Hai An, Claudine Rosario B Lukban, Gerald Marion M Abesamis, Ralf V Santamaria, Fernando A Acance, Deni Alia Yadi, Amelia Ganefianty, Abdurrahman Hakim, Chamath Sachindra Angulugaha, Gayan Ekanayake, Svp Wimalarathna, Mohd Shahrul Suondoh, Salmi Mohamed Sukur, Thanchanock Sawangsangwattana, Tippawan Wattanakham, Amarmend Ganbat
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Abstract
This case-series supplement serves as an educational resource for health professionals involved in the care of burn injuries. Drawing from clinical experiences across healthcare settings in the Asia-Pacific region, the supplement focuses on the use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) solution, gel and high-viscosity gel, alone or in combination, in managing both thermal and non-thermal burns, including partial-thickness and full-thickness burns, in both paediatric and adult populations. In alignment with international guidance, this supplement reinforces the recommendation to integrate PHMB-B into routine practice. The broad-spectrum antimicrobial activity, low cytotoxicity and biofilm-disruptive properties of this combined solution is clinically appropriate for use in complex burn wounds, where infection control and optimal healing conditions are crucial to wound healing.
期刊介绍：
Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice.
In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers.
Specifically, JWC publishes:
High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more
The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide
In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments
Clinical case studies providing information on how to deal with complex wounds
Comprehensive literature reviews on current concepts and practice, including cost-effectiveness
Updates on the activities of wound care societies around the world.
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