Clinical and neurophysiological effects of rTMS on chronic post-stroke hand spasticity

IF 2.4 4区医学 Q2 CLINICAL NEUROLOGY

Neurophysiologie Clinique/Clinical Neurophysiology Pub Date : 2026-02-01 Epub Date: 2025-12-04 DOI:10.1016/j.neucli.2025.103125

José Luis Guerrero Solano , Oscar Ayo-Martin , Tomas Segura

引用次数: 0

Abstract

This observational open-label study evaluates the clinical and neurophysiological effects of multiple sessions of contralesional motor cortex low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) on seventeen patients with chronic post-stroke hand spasticity. Results: LF-rTMS improved spasticity (Modified Ashworth Scale, p < 0.001), strength (tip pinch, p = 0.002; grip force, p < 0.001), flexibility (finger tapping test, p = 0.014; tapping test, p = 0.008), motor threshold difference (p < 0.001), and motor evoked potential latency (p = 0.004), with no adverse events reported. Improvement in spasticity persisted after 3 months. Conclusion: LF-rTMS is a safe and effective therapy for chronic post-stroke hand spasticity.

查看原文本刊更多论文

rTMS对脑卒中后慢性手部痉挛的临床和神经生理影响

这项开放标签的观察性研究评估了对侧运动皮层低频重复经颅磁刺激（LF-rTMS）对17例脑卒中后慢性手部痉挛患者的临床和神经生理效果。结果：LF-rTMS改善了痉挛（改良Ashworth量表，p < 0.001）、力量（指尖捏，p = 0.002；握力，p < 0.001）、柔韧性（手指叩击试验，p = 0.014；叩击试验，p = 0.008）、运动阈值差（p < 0.001）和运动诱发电位潜伏期（p = 0.004），无不良事件报告。痉挛改善持续3个月。结论：LF-rTMS是一种安全有效的治疗脑卒中后慢性手部痉挛的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Neurophysiologie Clinique/Clinical Neurophysiology 医学-临床神经学

CiteScore

5.20

自引率

3.30%

发文量

审稿时长

60 days

期刊介绍： Neurophysiologie Clinique / Clinical Neurophysiology (NCCN) is the official organ of the French Society of Clinical Neurophysiology (SNCLF). This journal is published 6 times a year, and is aimed at an international readership, with articles written in English. These can take the form of original research papers, comprehensive review articles, viewpoints, short communications, technical notes, editorials or letters to the Editor. The theme is the neurophysiological investigation of central or peripheral nervous system or muscle in healthy humans or patients. The journal focuses on key areas of clinical neurophysiology: electro- or magneto-encephalography, evoked potentials of all modalities, electroneuromyography, sleep, pain, posture, balance, motor control, autonomic nervous system, cognition, invasive and non-invasive neuromodulation, signal processing, bio-engineering, functional imaging.